Purified anti-human CD1d Antibody

Pricing & Availability
51.1 (See other available formats)
Regulatory Status
Other Names
Mouse IgG2b, κ
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Product Citations
Human peripheral blood lymphocytes stained with CD19 FITC and purified CD1d (51.1) conjugated with PE (top) or mouse IgG2b PE isotype control (bottom)
  • 51.1_PE__1_090310
    Human peripheral blood lymphocytes stained with CD19 FITC and purified CD1d (51.1) conjugated with PE (top) or mouse IgG2b PE isotype control (bottom)
  • 51.1_PE__2_090310
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350302 100 µg £73
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CD1d is a MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily. On the cell surface, CD1d forms a heterodimer with β2-microglobulin. CD1d is expressed by antigen-presenting cells such as B cells, monocytes/macrophages, dendritic cells, and some non-lymphoid cells. Cortical thymocytes express CD1d but the expression is lost in mature T cells. CD1d presents lipid antigens to iNKT cells analogous to MHC molecule presentation of peptides to T cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Reported Reactivity
Antibody Type
Host Species
Human CD1d-Fc fusion
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IHC-F, IP, Stim, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1, Western blotting1,2, and induction of IL-12 production by crosslinking of CD1d3.

Application References

(PubMed link indicates BioLegend citation)
  1. Exley M, et al. 2000. Immunology 100:37. (IHC, WB)
  2. Durante-Mangoni E, et al. 2004. J. Immunol. 173:2159. (WB)
  3. Yue SC, et al. 2005. P. Natl. Acad. Sci. USA 102:11811. (Stim)
Product Citations
  1. Frasca D, et al. 2020. Front Immunol. 11:392. PubMed
  2. Guo T, et al. 2018. J Immunol. 200:500. PubMed
AB_10641848 (BioLegend Cat. No. 350302)

Antigen Details

MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily

Expressed by cortical thymocytes, monocytes, macrophages, dendritic cells, B cells (highly expressed on marginal zone B cells in particular), and in some non-lymphoid cells

Present lipid antigens to iNKT cells
When loaded with a lipid, is recognized by the Vα14i TCR from iNKT cells
Cell Type
B cells, Dendritic cells, Macrophages, Monocytes, Thymocytes
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, MHC Antigens, TCRs
Antigen References

1. Koch M, et al. 2005. Nat. Immunol. 6:819.
2. Liu X, et al. 2010. P. Natl. Acad. Sci. USA 107:13010.
3. Zeissig S, et al. 2010. J. Clin. Invest. 120:2889.
4. Teige A, et al. 2010. J. Immunol. 185:345.

Gene ID
912 View all products for this Gene ID
View information about CD1d on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 3    Revision Date: 08/23/2022

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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