- LSB2.20 (See other available formats)
- Other Names
- SIRPgamma, Signal regulatory protein β2 (SIRPβ2)
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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Signal Regulatory Proteins (SIRPs) comprise a family of several transmembrane glycoproteins (SIRPα, SIRPβ, and SIRPγ) that belong to immunoglobulin superfamily. SIRPγ is also known as CD172g or SIRPβ2 which is primarily expressed on T cells and a subpopulation of B cells. Like CD172a, the ligand of CD172g is CD47. But the binding affinity with CD172g is lower than CD172a. The biological functions of CD172g include regulation of T-cell transendothelial migration and induction of T cell apoptosis.Product Details
- Human, African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications include: blocks T-cell transendothelial migration
(PubMed link indicates BioLegend citation)
- Stefanidakis M, et al. 2008. Blood 112:1280
- Product Citations
AB_1227768 (BioLegend Cat. No. 336602)
- Transmembrane glycoprotein, Ig superfamily
T cells, B cell subset
- Regulate T-cell transendothelial migration, induce T cell apoptosis
- Cell Type
- B cells, T cells
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers
2. Brooke G, et al. 2004. J. Immunol. 173:2562
- Gene ID
- 55423 View all products for this Gene ID
- View information about CD172g on UniProt.org
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