Purified anti-HBα1 Antibody

Pricing & Availability
Clone
Poly28640 (See other available formats)
Other Names
Hemoglobin Subunit Alpha 1, Hemoglobin Alpha 1, HBA2
Isotype
Rabbit Polyclonal IgG
Ave. Rating
Submit a Review
Product Citations
publications
Poly28640_PURE_HBa1_Antibody_1_062519
Western blot of purified anti- HBα1 antibody (Poly28640). Lane 1: Molecular weight marker; Lane 2: 20 µg of human spleen lysate; Lane 3: 20 µg of human plasma. The blot was incubated with 0.05 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP-labeled donkey anti-rabbit IgG (Cat. No. 406401). Enhanced chemiluminescence was used as the detection system. Note that human plasma is depleted of red blood cell and thus used as negative control.
  • Poly28640_PURE_HBa1_Antibody_1_062519
    Western blot of purified anti- HBα1 antibody (Poly28640). Lane 1: Molecular weight marker; Lane 2: 20 µg of human spleen lysate; Lane 3: 20 µg of human plasma. The blot was incubated with 0.05 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP-labeled donkey anti-rabbit IgG (Cat. No. 406401). Enhanced chemiluminescence was used as the detection system. Note that human plasma is depleted of red blood cell and thus used as negative control.
Cat # Size Price Quantity Avail. Save
864001 25 µg £64
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

HBα1 (Hemoglobin alpha 1) is a component of the complex that forms hemoglobin in the red blood cells, which carries and transports oxygen to the peripheral tissues. Deletions of HBα1 lead to a genetic disorder called alpha thalassemia, a blood disorder in which hemoglobin production is reduced.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Polyclonal
Host Species
Rabbit
Immunogen
Recombinant HBα1 (Met1~Arg142) with N-terminal His-Tag
Formulation
0.01 M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.05 - 1.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Antigen Details

Structure
HBα1 is a 142 amino acid protein with predicted and observed molecular mass of ~15 kD.
Distribution

Tissue Distribution: Bone marrow and spleen
Cellular Distribution: Extracellular and cytosol

Function
HBα1 is a component of the hemoglobin complex that carries oxygen.
Interaction
HBα1 forms heterotetramer with HBβ1.
Biology Area
Angiogenesis
Molecular Family
Blood Group Markers, Carrier Proteins
Antigen References
  1. Patrinos GP, et al. 2005. Hum Mutat. 26(5):399
  2. Standing SJ, et al. 1992. Ann Clin Biochem. 29:494
  3. Koslowski H, et al. 1990. Padiatr Grenzgeb. 29(1):25
Gene ID
3039 View all products for this Gene ID 3040 View all products for this Gene ID
UniProt
View information about HBalpha1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 06/25/2019

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Login / Register
Forgot your password? Reset password?
Create an Account