- AN4.3 (See other available formats)
- Regulatory Status
- Other Names
- Mouse IgG2a
- Ave. Rating
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- Product Citations
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Cyclin-dependent kinase 2 (Cdk2), also known as cell division protein kinase 2, is an enzyme involved in cell cycle control. Binding of Cdk2 to Cyclin E in G1 phase is required for G1 to S phase transition, while binding of Cdk2 to Cyclin A is required to progress through the S phase. Clone AN4.3 does not recognize other CDKs.Product Details
- Human, Mouse
- Antibody Type
- Host Species
- CDK2 recombinant protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
(PubMed link indicates BioLegend citation)
- Shi L, et al. 2014. J. Immunol. 192:649. PubMed
- Product Citations
AB_2276103 (BioLegend Cat. No. 643901)
- There are two isoforms reported in human with predicted MW of 30 kD, 34 kD, respectively; there are also two isoforms reported in mouse with predicted MW of 34 kD, 39 kD, respectively.
Nuclear protein, predicted molecular weight 34 kD.
- Involved in the control of the cell cycle
- Cyclins A, B1, B3, D, or E.
- Biology Area
- Cell Biology, Cell Cycle/DNA Replication
- Antigen References
1. Jeffrey PD, et al. 1995. Nature 376:313
- Gene ID
- 1017 View all products for this Gene ID
- View information about Cdk2 on UniProt.org
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