PerCP/Cyanine5.5 anti-human TCR Vβ1 Antibody

Pricing & Availability
Clone
BL37.2 (See other available formats)
Regulatory Status
RUO
Other Names
TCRBV1S1, TCRBV9
Isotype
Rat IgG1, κ
Ave. Rating
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Product Citations
publications
BL37.2_APC_TCRBV1_Antibody_FC_1_082013.jpg
Human peripheral blood lymphocytes were stained with CD3 APC and anti-human TCR Vβ1 (clone BL37.2 PerCP/Cyanine5.5 (top) or rat IgG1, κ PerCP/Cyanine5.5 isotype control (bottom).
  • BL37.2_APC_TCRBV1_Antibody_FC_1_082013.jpg
    Human peripheral blood lymphocytes were stained with CD3 APC and anti-human TCR Vβ1 (clone BL37.2 PerCP/Cyanine5.5 (top) or rat IgG1, κ PerCP/Cyanine5.5 isotype control (bottom).
  • BL37.2_APC_TCRBV1_Antibody_FC_2_082013.jpg
See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
360103 25 tests £113
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360104 100 tests £245
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Cat. No. 360103 is scheduled for discontinuation. Please use the availability checker to determine current availability. The larger size is available as an alternative.
Description

TCR Vβ1 is a variant of the TCR Vβ chain that is expressed by a subset of αβ+ T cells. Aberrant expression of TCR Vβ chains has been associated with infection and cancer. TCR Vβ1 is reported to be preferably used by autoreactive T cells in a model of autoimmune thyroiditis and diabetes. Skewing of TCR Vβ repertoire to Vβ1 and Vβ9 has also been reported in patients with multiple sclerosis, reactive arthritis, and Kawasaki disease.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Rat cell line RBL-2H3 transfected with human TCR-VB1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Additional Product Notes

BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.

RRID
AB_2562496 (BioLegend Cat. No. 360103)
AB_2562497 (BioLegend Cat. No. 360104)

Antigen Details

Structure
Disulfide-linked 80 kD heterodimer consisting of an α and β chain
Distribution

Subset of αβ+ T cells

Function
Recognize antigens bound to MHC molecules
Ligand/Receptor
Antigen bound MHC molecules
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References

1. Cihak J, et al. 1991. Proc. Natl. Acad. Sci. 88:10951.
2. Wei S, et al. 1994. Immunogenetics. 40:27.
3. Dunon D, et al. 1994. EMBO J. 13:808.

Gene ID
6957 View all products for this Gene ID
UniProt
View information about TCR Vbeta1 on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Go To Top Version: 1    Revision Date: 09/06/2013

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • PerCP/Cyanine5.5 anti-human TCR Vβ1

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