- RM134L (See other available formats)
- Regulatory Status
- Other Names
- OX-40L, CD134L, CD252, TNFSF4
- Rat IgG2b, κ
- Ave. Rating
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- Product Citations
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CD252 is a 35 kD member of the TNF superfamily and is also known as OX40 ligand, OX40L, and CD134L. The CD252 is expressed on activated B cells and antigen presenting cells. CD252 interacts with OX40 antigen (CD134), expressed predominantly on activated T cells to increase proliferation and IL-2 production and to enhance proliferation and immunoglobulin secretion in activated B cells.Product Details
- Antibody Type
- Host Species
- Rat NRK-52E cell line transfected with mouse OX-40L
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
The RM134L antibody can block the costimulatory activity of OX40L. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections3, and in vivo and in vitro blocking of OX-40L-OX-40 functional interaction1,2,4. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 108808).
(PubMed link indicates BioLegend citation)
- Akiba H, et al. 1999. J. Immunol. 162:7058. (Block)
- Akiba H, et al. 2000. J. Exp. Med. 191:375. (Block)
- Hoshino A, et al. 2003. Eur. J. Immunol. 33:861. (IHC)
- Terrazas LI, et al. 2005. Intl. J. Parasitology. 35:1349. (Block)
- Zheng X, et al. 2010. Invest Ophthalmol Vis Sci. 51:3076. PubMed
AB_2819816 (BioLegend Cat. No. 108815)
AB_2819817 (BioLegend Cat. No. 108816)
- NGF/TNF superfamily, 35 kD
Activated B cells, antigen presenting cells
- B-cell/T-cell interaction, costimulation
- OX40 (CD134)
- Cell Type
- Antigen-presenting cells, B cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules, Immune Checkpoint Receptors
- Antigen References
1. Akiba H, et al. 1999. J. Immunol. 162:7058.
2. Stüber E, et al. 1995. Immunity 2:507.
3. Baum PR, et al. 1994. EMBO J. 13:3992.
- Gene ID
- 22164 View all products for this Gene ID
- View information about CD252 on UniProt.org
|Biotin anti-mouse CD252 (OX40L)||RM134L||FC|
|PE anti-mouse CD252 (OX40L)||RM134L||FC|
|Purified anti-mouse CD252 (OX40L)||RM134L||FC, IHC-F, Block|
|Alexa Fluor® 647 anti-mouse CD252 (OX40L)||RM134L||FC|
|APC anti-mouse CD252 (OX40L)||RM134L||FC|
|PE/Cyanine7 anti-mouse CD252 (OX40L)||RM134L||FC|
|PE/Dazzle™ 594 anti-mouse CD252 (OX40 Ligand)||RM134L||FC|
|TotalSeq™-C0924 anti-mouse CD252 (OX40 Ligand)||RM134L||PG|
|Ultra-LEAF™ Purified anti-mouse CD252 (OX40 Ligand)||RM134L||FC, IHC-F|
|TotalSeq™-B0924 anti-mouse CD252 (OX40 Ligand) Antibody||RM134L||PG|
|TotalSeq™-A0924 anti-mouse CD252 (OX40 Ligand)||RM134L||PG|
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Biotin anti-mouse CD252 (OX40L)
PE anti-mouse CD252 (OX40L)
Purified anti-mouse CD252 (OX40L)
Alexa Fluor® 647 anti-mouse CD252 (OX40L)
APC anti-mouse CD252 (OX40L)
PE/Cyanine7 anti-mouse CD252 (OX40L)
PE/Dazzle™ 594 anti-mouse CD252 (OX40 Ligand)
TotalSeq™-C0924 anti-mouse CD252 (OX40 Ligand)
Ultra-LEAF™ Purified anti-mouse CD252 (OX40 Ligand)
TotalSeq™-B0924 anti-mouse CD252 (OX40 Ligand) Antibody
TotalSeq™-A0924 anti-mouse CD252 (OX40 Ligand)