PE/Cy7 anti-human CD110 Antibody

Pricing & Availability
Clone
S16017E (See other available formats)
Other Names
TPOR, c-MPL, MPLV
Isotype
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
S16017E_PECy7_CD110_Antibody_101818
Resting human platelets were stained with PE/Cy7 anti-human CD110 (clone S16017E; filled histogram) or with PE/Cy7 mouse IgG2a, κ isotype control (open histogram).
  • S16017E_PECy7_CD110_Antibody_101818
    Resting human platelets were stained with PE/Cy7 anti-human CD110 (clone S16017E; filled histogram) or with PE/Cy7 mouse IgG2a, κ isotype control (open histogram).
See PE/Cy7 spectral data
Cat # Size Price Quantity Avail. Save
393709 25 tests £97
Check Availability


Need larger quantities of this item?
Request Bulk Quote
393710 100 tests £208
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD110 is a type I transmembrane glycoprotein which functions as a receptor for thrombopoietin; binding causes the proliferation and differentiation of megakaroyocytes in addition to the production of platelets and protection of stem cells from apoptosis. CD110 is primarily expressed on hematopoietic stem cells, hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CD110 transfectants
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2783302 (BioLegend Cat. No. 393709)
AB_2783303 (BioLegend Cat. No. 393710)

Antigen Details

Structure
Type I transmembrane glycoprotein
Distribution

Hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets.

Function
Megakaryocytopoiesis and platelet formation
Interaction
THPO, ATXN2L, JAK2
Ligand Receptor
Thrombopoietin
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References
  1. Ninos JM, et al. 2006. J. Transl. Med. 16:4-9.
  2. Broudy VC, et al. 1996. Blood. 88:2026-32.
  3. Wang X, et al. 2016. Blood. 127:3398-409.
Gene ID
4352 View all products for this Gene ID
UniProt
View information about CD110 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 10/19/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 9727 Pacific Heights Blvd, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Login / Register
Forgot your password? Reset password?
Create an Account