- 2E9/CCL5 (See other available formats)
- Regulatory Status
- Other Names
- CCL5, SISd, Scya5, RANTES, TCP228
- Mouse IgG2b, κ
- Ave. Rating
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- Product Citations
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Chemokine (C-C motif) ligand 5 (CCL5), also known as regulated on activation, normal T cell expressed and secreted (RANTES), is a 10 kD protein primarily produced by CD8+ T cells. CCL5 can also be secreted by platelets, dendritic cells (DCs), and fibroblasts. CCL5 functions as a chemoattractant for T cells, monocytes, and eosinophils through binding of its receptor, CCR5. CCL5 can inhibit binding of HIV-1 to CCR5 and inhibit HIV-1 entry.Product Details
- Antibody Type
- Host Species
- Recombinant CCL5
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
(PubMed link indicates BioLegend citation)
- Jubin V, et al. 2012. Immunol. Res. 52:284.
- Product Citations
AB_2832528 (BioLegend Cat. No. 149105)
AB_2860706 (BioLegend Cat. No. 149106)
- Chemokine (C-C motif) ligand 5, 10 kD
CD8+ T cells, platelets, DCs, and fibroblasts.
- Chemoattractant for T cells, monocytes, and eosinophils.
- CCR5, CCR3, and CCR1.
- Cell Type
- B cells, Dendritic cells, Granulocytes, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Antigen References
1. Schall TJ. 1991. Cytokine 3:165.
2. Schall TJ, et al. 1992. Eur. J. Immunol. 6:1477.
3. Son MH, et al. 2014. Biochem. Biophys. Res. Commun. 450:30.
- Gene ID
- 20304 View all products for this Gene ID
- View information about CCL5 on UniProt.org
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