- S18012C (See other available formats)
- Regulatory Status
- Other Names
- FcγRI, FcR I
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Recombinant human CD64-Fc (1257-FC-050)
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
AB_2904422 (BioLegend Cat. No. 399507)
AB_2904422 (BioLegend Cat. No. 399508)
- Ig superfamily, type I glycoprotein, 72 kD
Monocytes, macrophages, dendritic cells, activated granulocytes
- Phagocytosis, ADCC
- IgG receptor
- Cell Type
- Dendritic cells, Granulocytes, Macrophages, Monocytes
- Biology Area
- Immunology, Inhibitory Molecules
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
- Hulett MD & Hogarth PM. 1994. Adv Immunol. 57:1-127.
- van de Winkel JG & Capel PJ. 1993. Immunol Today. 14:215-21.
- Gene ID
- 2209 View all products for this Gene ID
- View information about CD64 on UniProt.org
Related Pages & Pathways
Other FormatsView All CD64 Reagents Request Custom Conjugation
|FITC anti-human CD64||S18012C||FC|
|PE anti-human CD64||S18012C||FC|
|Purified anti-human CD64||S18012C||FC|
|APC anti-human CD64||S18012C||FC|
|PE/Cyanine7 anti-human CD64||S18012C||FC|
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