- S15040E (See other available formats)
- Other Names
- CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1
- Rat IgG2b, κ
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- Product Citations
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CD191, also known as CCR1, is a seven transmembrane G protein coupled receptor. It is involved in protecting the host from inflammatory responses and viral/parasite invasion, ligands include macrophage inflammatory protein 1 alpha (MIP-1 alpha, ), regulated on activation normal T expressed and secreted protein (RANTES, CCL5), monocyte chemoattractant protein 3 (MCP-3, CCL7), and myeloid progenitor inhibitory factor-1 (MPIF-1, CCL23).Product Details
- Antibody Type
- Host Species
- Mouse CCR1-transfectants.
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- 41KD, seven transmembrane protein.
Macrophages, monocytes, neutrophils and eosinophils.
- Regulating migration of cells in response to CCL3, CCL5, CCL7 and CCL23.
- Ligand Receptor
- CCL3, CCL5, CCL7 and CCL23.
- Cell Type
- Eosinophils, Macrophages, Monocytes, Neutrophils
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Lionakis MS, et al. 2012. PLoS Pathog. 8:e1002865.
2. Gilliland CT, et al. 2013. J. Biol. Chem. 288:32194.
3. Gong X, et al. 1997. J. Biol. Chem. 272:11682.
4. Daugherty BL, Springer MS. 1997. Genomics. 41:294.
5. Pakianathan DR, et al. 1997. Biochemistry 36:9642.
- Gene ID
- 12768 View all products for this Gene ID
- View information about CD191 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
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