PE anti-mouse CD191 (CCR1) Antibody

Pricing & Availability
Clone
S15040E (See other available formats)
Other Names
CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
S15040E_PE_CD191_Antibody_011019
Thioglycollate-elicited BALB/c mouse peritoneal macrophages were stained with CD191 (clone S15040E) PE (filled histogram) or rat IgG2b, κ PE isotype control (open histogram).
  • S15040E_PE_CD191_Antibody_011019
    Thioglycollate-elicited BALB/c mouse peritoneal macrophages were stained with CD191 (clone S15040E) PE (filled histogram) or rat IgG2b, κ PE isotype control (open histogram).
See PE spectral data
Cat # Size Price Quantity Avail. Save
152507 25 µg £94
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152508 100 µg £249
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Description

CD191, also known as CCR1, is a seven transmembrane G protein coupled receptor. It is involved in protecting the host from inflammatory responses and viral/parasite invasion, ligands include macrophage inflammatory protein 1 alpha (MIP-1 alpha, ), regulated on activation normal T expressed and secreted protein (RANTES, CCL5), monocyte chemoattractant protein 3 (MCP-3, CCL7), and myeloid progenitor inhibitory factor-1 (MPIF-1, CCL23).

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CCR1-transfectants.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Antigen Details

Structure
41KD, seven transmembrane protein.
Distribution

Macrophages, monocytes, neutrophils and eosinophils.

Function
Regulating migration of cells in response to CCL3, CCL5, CCL7 and CCL23.
Ligand Receptor
CCL3, CCL5, CCL7 and CCL23.
Cell Type
Eosinophils, Macrophages, Monocytes, Neutrophils
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Lionakis MS, et al. 2012. PLoS Pathog. 8:e1002865.
2. Gilliland CT, et al. 2013. J. Biol. Chem. 288:32194.
3. Gong X, et al. 1997. J. Biol. Chem. 272:11682.
4. Daugherty BL, Springer MS. 1997. Genomics. 41:294.
5. Pakianathan DR, et al. 1997. Biochemistry 36:9642.

Gene ID
12768 View all products for this Gene ID
UniProt
View information about CD191 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 01/10/2019

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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