PE anti-human MUC-17 Antibody

Pricing & Availability
Clone
MQ155 (See other available formats)
Other Names
Mucin-17, MUC3, MUC-3
Isotype
Mouse IgG1, κ
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Product Citations
publications
MQ155_PE_MUC-17_Antibody_062819.png
Human pancreatic cancer cell line (AsPC-1) stained with PE MUC-17 (Clone MQ155, filled histogram) or PE mouse IgG1, κ isotype control (open histogram).
  • MQ155_PE_MUC-17_Antibody_062819.png
    Human pancreatic cancer cell line (AsPC-1) stained with PE MUC-17 (Clone MQ155, filled histogram) or PE mouse IgG1, κ isotype control (open histogram).
See PE spectral data
Cat # Size Price Quantity Avail. Save
395303 25 tests £87
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395304 100 tests £202
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Description

It is a 451 KD glycocylated member of the mucin family with 2 EGF like domains on the C-terminus and serine/tyrosine phosphorylation sites on the cytoplasmic domain. It is expressed by epithelial cells and plays a role in cytoprotection, signal transduction. Expression of this molecule can also render tumor cells to become less adhesive. It interacts with PKDZ1 and increased expression of this molecule has been reported in colon cancer.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified Recombinant Muc17 protein, Freund’s Complete Adjuvant
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Antigen Details

Structure
451 KD N-glycosylate single pass membrane protein
Distribution

Gastrointestinal tract

Function
Cytoprotection, extravasation, signal transduction
Interaction
PDZK1
Biology Area
Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity
Antigen References
  1. Malmberg EK, et al. 2008. Biochem J. 410:283.
  2. Gum JR Jr, et al. 2002. Biochem Biophys Res Commun. 291:466.
  3. Hirono S, et al. 2010. Cancer Sci. 101:259.
Gene ID
140453 View all products for this Gene ID
UniProt
View information about MUC-17 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 06/28/2019

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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