Analyte Specific Reagent. Analytical and performance characteristics are not established.
- Other Names
- Interleukin-4, Ia inducing factor (IaIF), B-cell stimulating factor-1 (BSF-1), Hodgkin's cell growth factor (HCGF), Mast cell growth factor-2 (MCGF-2), Macrophage fusion factor (MFF), T cell growth factor-2 (TCGF-2)
- Rat IgG1, κ
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IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.Product Details
- Phosphate-buffered solution, pH7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), and a stabilizer.
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- 25 µg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Suggested for Intracellular Staining for Flow Cytometry
WARNINGS AND PRECAUTIONS
- Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet.
- This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal.
- All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations.
- Do not use this reagent beyond the expiration date stated on the label.
- Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration.
- Avoid prolonged exposure of the reagent or stained cells to light.
- Antigen References
- Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press San Diego.
- Boulay J and Paul WE. 1992. Curr Opin Immunol. 4:294-8.
- Dullens H and De Wit CL. 1991. In Vivo. 5:567-70.
- Paul W. 1991. Blood. 77:1859-70.
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APC anti-human IL-4
Biotin anti-human IL-4
FITC anti-human IL-4
PE anti-human IL-4
Purified anti-human IL-4
Alexa Fluor® 488 anti-human IL-4
Alexa Fluor® 647 anti-human IL-4
Brilliant Violet 421™ anti-human IL-4
PerCP/Cyanine5.5 anti-human IL-4
PE/Cyanine7 anti-human IL-4
Brilliant Violet 605™ anti-human IL-4
Purified anti-human IL-4 (Maxpar® Ready)
PE/Dazzle™ 594 anti-human IL-4
APC/Cyanine7 anti-human IL-4
Brilliant Violet 510™ anti-human IL-4
Ultra-LEAF™ Purified anti-human IL-4
TotalSeq™-B1149 anti-human IL-4
PE anti-human IL-4