PE anti-human Dopamine Receptor D1 Antibody

Pricing & Availability
Clone
L205G1 (See other available formats)
Regulatory Status
RUO
Other Names
DADR, DRD1A
Isotype
Mouse IgG2b, κ
Ave. Rating
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Product Citations
publications
L205G1_PE_Dopamine_Receptor_D1_Antibody_FC_030515
Human DRD1-transfected cells were stained with anti-DRD1 (clone L205G1) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).
  • L205G1_PE_Dopamine_Receptor_D1_Antibody_FC_030515
    Human DRD1-transfected cells were stained with anti-DRD1 (clone L205G1) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).
See PE spectral data
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366403 25 tests £86.00
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366404 100 tests £202.00
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Description

Dopamine receptors are a family of G protein-coupled receptors, which is composed of at least five (D1-D5) members. The D1 subtype is the most common receptor in the central nervous system. It is primarily expressed in caudate putamen in humans. This receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. It plays a role in neuronal growth and development along with behavioral responses. The D1 receptor also modulates D2-mediated events. There are two variants of this gene due to alternate transcription initiation sites.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human DRD1-transfectants.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Bellon A, et al. 2019. Front Mol Neurosci. 11:323. PubMed
RRID
AB_2565469 (BioLegend Cat. No. 366403)
AB_2565470 (BioLegend Cat. No. 366404)

Antigen Details

Structure
G protein-coupled receptor.
Distribution

DRD1 Transfected cells.

Function
Stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases.
Ligand/Receptor
Dopamine.
Cell Type
Dopaminergic Neurons
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
Molecular Family
CD Molecules, GPCR, Postsynaptic proteins
Antigen References

1. Fresnoza S, et al. 2014. J. Neurosci. 34(7):2744.
2. Mizuta K, et al. 2013. Respir. Res. 14:89.
3. Zhu F, et al. 2013. PLoS One 8(8):e70805.
4. Levy F, et al. 2013. J. Child Adolesc. Psychopharmacol. 6:423.

Gene ID
1812 View all products for this Gene ID
UniProt
View information about Dopamine Receptor D1 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 03/05/2015

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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