- 19F2 (See other available formats)
- Regulatory Status
- Other Names
- BCM, TNFRSF17
- Mouse IgG2a, κ
- Ave. Rating
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- Product Citations
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CD269, also known as B cell maturation antigen (BCMA), is a 27 kD, single pass transmembrane protein with one TNFR-Cys repeat on its extracellular domain. CD269 is a B cell maturation factor, essential for the long-term survival of plasma cells. It is expressed by plasmablasts, plasma cells, and germinal center B cells. The ligands of CD269 are BAFF and APRIL, and its cytoplasmic domain binds several of the TRAF family members.Product Details
- Antibody Type
- Host Species
- BCMA-mouse IgG Fc fusion protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with KIRAVIA Blue 520™ under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* KIRAVIA Blue 520™ has an excitation maximum of 495 nm, and a maximum emission of 520 nm.
KIRAVIA Blue™ 520 is a trademark of Sony. This product is subject to proprietary rights of Sony and is made and sold under license from Sony Corporation. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Sony and the Sony logo are registered trademarks of Sony Corporation.
- Excitation Laser
Blue Laser (488 nm)
AB_2890787 (BioLegend Cat. No. 357527)
AB_2890787 (BioLegend Cat. No. 357528)
- Single pass transmembrane protein, member of the TNFR superfamily, 1 TNFR-Cys domain, 27 kD
Plasmablasts, plasma cells, germinal center B cells
- B cell maturation factor, essential for survival of plasma cells
- Associates with several TRAF family members
- BAFF, APRIL
- Cell Type
- B cells, Plasma cells
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Coquery CM and Erickson LD. 2012. Crit. Rev. Immunol. 32:287.
2. Notas G, et al. 2012. J. Immunol. 189:4748.
3. Rickert RC, et al. 2011. Immunol. Rev. 244:115.
4. Mesin L, et al. 2011. J. Immunol. 187:2867.
- Gene ID
- 608 View all products for this Gene ID
- View information about CD269 on UniProt.org
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