- Clone
- HIP2 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- HCDM listed
- Other Names
- ITGA2B, Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, CD41
- Isotype
- Mouse IgG3, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood platelets stained with CD41b (clone HIP2) FITC (filled histogram) or anti-mouse IgG3 FITC isotype control.
| Cat # | Size | Price | Quantity Avail. | Save | ||
|---|---|---|---|---|---|---|
| 354804 | 100 tests | £154 | ||||
CD41b is a β chain of glycoprotein IIb (known as CD41) which is associated with glycoprotein IIIa (or integrin β3, CD61) and forms CD41/CD61 complex. CD41/CD61 mediates platelet adhesion and aggregation through the interaction with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is expressed by platelets and megakaryocytes.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
-
Application References
(PubMed link indicates BioLegend citation) -
- Leong L, et al. 1995. J. Cell. Sci. 108:3817.
- RRID
-
AB_11219382 (BioLegend Cat. No. 354804)
Antigen Details
- Structure
- A β chain of glycoprotein IIb that associates with glycoprotein IIIa to form a CD41/CD61 complex
- Distribution
-
Platelets, Megakaryocytes
- Function
- Platelet activation and aggregation
- Cell Type
- Megakaryocytes, Platelets
- Biology Area
- Angiogenesis, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules, Protein Kinases/Phosphatase
- Antigen References
-
1. Nakahata T, et al. 1994 Leuk. Lymphoma 13:401.
- Gene ID
- 3674 View all products for this Gene ID
- UniProt
- View information about CD41b on UniProt.org
Related FAQs
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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