- CBR LFA-1/2 (See other available formats)
- Regulatory Status
- Other Names
- Integrin β2 subunit, LFA -1 β subunit, β2 integrin, ITGB2, b2 integrin, beta 2 integrin
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
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CD18, also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin, is a 90 - 95 kD type I glycoprotein. CD18 non-covalently associates with CD11a, CD11b, or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in the adhesion and signaling in hematopoietic cells.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Purified human LFA-1
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats of this clone) include: activation of LFA-1 and MAC-11,2. The LEAF™ or Ultra-LEAF™ purified antibody (Endotoxin < EU/µg, Azide-Free, 0.2 µm filtered) is recommended for function assays (contact our custom solutions team).
(PubMed link indicates BioLegend citation)
- Petruzzelli L, et al. 1995. J. Immunol. 155:854. (Activ)
- Lu C, et al. 2001. J. Immunol. 166:5629. (Activ)
AB_2565529 (BioLegend Cat. No. 366305)
AB_2565530 (BioLegend Cat. No. 366306)
- 90 - 95 kD type I transmembrane glycoprotein.
- Cell adhesion and signaling.
- Integrin, type I transmembrane glycoprotein, associates with CD11a, CD11b, or CD11c
- Cell Type
- Biology Area
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175.
2. Springer TA. 1994. Cell 76:301.
- Gene ID
- 3689 View all products for this Gene ID
- View information about CD18 on UniProt.org
|Purified anti-human CD18||CBR LFA-1/2||FC|
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