- NK92.39 (See other available formats)
- Regulatory Status
- Other Names
- Tactile (T cell-activated increased late expression)
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD96, known as TACTILE (T cell-activated increased late expression), is a 160 kD type I transmembrane glycoprotein and is a member of the Ig superfamily molecules. It is expressed on NK cells, T cells (up-regulated upon activation), and some acute myeloid leukemia (AML) cells, but not on normal B and myeloid cells. A soluble form of CD96 has been found in serum. CD96 is involved in T- and NK-cell adhesion through interaction with its ligand, CD155 (polio virus receptor).Product Details
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
- Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
- Excitation Laser
Violet Laser (405 nm)
- Application Notes
Additional reported applications include: block interaction of CD96 with PVR and functional assay
(PubMed link indicates BioLegend citation)
- Fuchs A, et al. 2004. J. Immunol. 172:3994
- Manes TD, et al. 2011. J. Immunol. 186:1763. PubMed
- Product Citations
AB_2629536 (BioLegend Cat. No. 338417)
AB_2629537 (BioLegend Cat. No. 338418)
- 160 kD, type I transmembrane protein, Ig superfamily
NK cells, T cells (upregulated upon activation)
- CD155 (PVR)
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity, Inhibitory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Hosen N, et al. 2007. Proc. Natl. Acad. Sci. USA 104:11008
3. Gong J, et al. 2008. Clin. Exp. Immunol.
- Gene ID
- 10225 View all products for this Gene ID
- View information about CD96 on UniProt.org
- What is the F/P ratio range of our BV421™ format antibody reagents?
It is lot-specific. On average it ranges between 2-4.
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