Biotin anti-mouse IL-25 (IL-17E) Antibody

Pricing & Availability
35B (See other available formats)
Regulatory Status
Other Names
Rat IgG1, κ
Ave. Rating
Submit a Review
Product Citations
Cat # Size Price Quantity Check Availability Save
514405 50 µg £103.00
Check Availability

Need larger quantities of this item?
Request Bulk Quote

IL-25 (IL-17E) is a member of the IL-17 family of proinflammatory cytokines which include at least six members including IL-17A (IL-17), IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. IL-17E is found at low levels in various peripheral tissues. It is a proinflammatory cytokine that promotes airway eosinophilia in mice. IL-17E plays a role in Th2 type inflammatory diseases, such as asthma and atopic dermatitis.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

ELISA Detection - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Neutralization: The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of mouse IL-25 bioactivity (Cat. No. 514417).

Application References

(PubMed link indicates BioLegend citation)
  1. Angkasekwinai P, et al. 2007. J. Exp Med. 204:1509.
Product Citations
AB_2124805 (BioLegend Cat. No. 514405)

Antigen Details

Cytokine; 19 kD
Induce proinflammatory responses, promote the expression of the prototypical Th2 genes
Cell Sources
Activated Th2 cells, bone marrow-derived mast cells, and alveolar macrophages
Cell Targets
IL-17RB mRNA transcripts are abundantly expressed in the kidney and liver and at lower levels in the testes, brain, small intestine, and other organs.
IL-17BR (EVI27, IL17Rh1)
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology, Innate Immunity, Signal Transduction
Molecular Family
Antigen References

1. Fort MM, et al. 2001. Immunity 15:985.
2. Lee J, et al. 2001. J. Biol Chem. 276:1660.
3. Hurst SD, et al. 2002. J. Immunol. 169:443.
4. Kleinschel MA, et al. 2007. J. Exp. Med. 204:161.

Gene ID
140806 View all products for this Gene ID
View information about IL-25 on

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 2    Revision Date: 05/22/2013

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Insert Note Here
Save Close Clear
Lab Timer
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account