- H5C6 (See other available formats)
- Regulatory Status
- HCDM listed
- Other Names
- LIMP, LAMP-3, Melanoma-associated antigen (ME491), Pltgp40, gp55
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
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CD63 is a 53 kD type III lysosomal glycoprotein also known as LIMP, LAMP-3, gp55, and melanoma-associated antigen (ME491). CD63 is a member of the tetraspan transmembrane superfamily (TM4SF) protein expressed on activated platelets, monocytes/macrophages, endothelium, fibroblasts, osteoclasts, and smooth muscle cells. CD63 may be involved in platelet activation and is thought to function as a transmembrane adaptor protein. CD63 has been shown to associate with CD9, CD81, VLA-3, and VLA-6.Product Details
- Verified Reactivity
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Host Species
- T cell line HPB-ALL
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: Western blotting1, immunofluorescence2, and immunoprecipitation1.
(PubMed link indicates BioLegend citation)
- Hildreth JE, et al. 1991. Blood 77:121. (IP, WB)
- Beatty WL, et al. 2006. J. Cell Sci. 119:350. (IF)
- Product Citations
AB_2561675 (BioLegend Cat. No. 353017)
AB_2561676 (BioLegend Cat. No. 353018)
- Tetraspan transmembrane superfamily (TM4SF), type III lysosomal glycoprotein, 53 kD
Activated platelets, monocytes, macrophages, endothelium, fibroblasts, osteoclasts, and smooth muscle
- Platelet activation
- CD9, CD81, VLA-3, and VLA-6
- Cell Type
- B cells, Endothelial cells, Fibroblasts, Macrophages, Monocytes, Osteoclasts, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
- Azorsa DO, et al. 1991. Blood 78:280.
- Kishimoto T, et al. Eds. 1997. Leukocyte Typing V1. Oxford University Press New York.
- Hildreth JE, et al. 1991. Blood 77:121.
- Anzai N, et al. 2002. Blood 99:4413.
- Gene ID
- 967 View all products for this Gene ID
- View information about CD63 on UniProt.org
Related Pages & Pathways
- How many biotin molecules are per antibody structure?
- We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Other FormatsView All CD63 Reagents Request Custom Conjugation
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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PE anti-human CD63
FITC anti-human CD63
Pacific Blue™ anti-human CD63
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PE/Cyanine7 anti-human CD63
Alexa Fluor® 647 anti-human CD63
Biotin anti-human CD63
PerCP/Cyanine5.5 anti-human CD63
PE/Dazzle™ 594 anti-human CD63
Brilliant Violet 421™ anti-human CD63
Brilliant Violet 650™ anti-human CD63
APC/Fire™ 750 anti-human CD63
Alexa Fluor® 700 anti-human CD63
Brilliant Violet 510™ anti-human CD63
Alexa Fluor® 594 anti-human CD63
TotalSeq™-A0404 anti-human CD63
Alexa Fluor® 488 anti-human CD63
Ultra-LEAF™ Purified anti-human CD63
Brilliant Violet 711™ anti-human CD63
Brilliant Violet 785™ anti-human CD63
APC/Cyanine7 anti-human CD63
TotalSeq™-B0404 anti-human CD63
TotalSeq™-C0404 anti-human CD63
Brilliant Violet 605™ anti-human CD63 Antibody
PE/Cyanine5 anti-human CD63 Antibody