APC/Cyanine7 anti-human CD195 (CCR5) Antibody

Pricing & Availability
J418F1 (See other available formats)
Regulatory Status
Other Names
C-C chemokine receptor type 5 (CCR5), HIV-1 fusion co-receptor
Rat IgG2b, κ
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Product Citations
Human peripheral blood lymphocytes were stained with CD4 FITC and CD195 (CCR5) (clone J418F1) APC/Cyanine7 (left) or Rat IgG2b, ? APC/Cyanine7 isotype control (right)
  • J418F1_APCCyanine7_CD195_Antibody_020619_updated.png
    Human peripheral blood lymphocytes were stained with CD4 FITC and CD195 (CCR5) (clone J418F1) APC/Cyanine7 (left) or Rat IgG2b, ? APC/Cyanine7 isotype control (right)
Compare all formats See APC/Cyanine7 spectral data
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359110 100 tests £245
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CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Human CCR5 transfectants
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Product Citations
  1. Muthuswamy R, et al. 2021. J Immunother Cancer. 9:. PubMed
  2. Liao Y, et al. 2018. Stem Cells Transl Med. 0.659722222. PubMed
AB_2562653 (BioLegend Cat. No. 359110)

Antigen Details

G-coupled receptor family 1, membrane protein, 45 kD

Subset of T cells, monocytes

Binds C-C chemokines and transduces an intracellular signal thought to result in proliferation and differentiation, acts as a co-receptor with CD4 for HIV-1
Cell Type
Monocytes, T cells
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Samson M, et al. 1996. Biochemistry 35:3362.
2. Raport CJ, et al. 1996. J. Biol. Chem. 271:17161.
3. Combadiere C, et al. 1996. J. Leukoc. Biol. 60:147.
4. Deng H, et al. 1996. Nature 381:661.
5. Lai J, et al. 2003. CVI. 10:1123.
6. Mañes S, et al. 2003. J. Exp. Med. 198:1381.
7. Vaday GG, et al. 2006. Prostate 66:124.

Gene ID
1234 View all products for this Gene ID
View information about CD195 on UniProt.org

Related FAQs

Does staining at room temperature or even at 37°C help for checking chemokine receptors expression?

Due to continuous recycling of many chemokine receptors, it may be worthwhile to consider staining at room temperature or at 37°C if the staining at lower temperature (which can potentially reduce receptor turnover) is not optimal.

Go To Top Version: 2    Revision Date: 02/06/2019

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human CD195 (CCR5)

  • Alexa Fluor® 488 anti-human CD195 (CCR5)

  • PE anti-human CD195 (CCR5)

  • PE/Cyanine7 anti-human CD195 (CCR5)

  • APC/Cyanine7 anti-human CD195 (CCR5)

  • PerCP/Cyanine5.5 anti-human CD195 (CCR5)

  • Alexa Fluor® 647 anti-human CD195 (CCR5)

  • Alexa Fluor® 700 anti-human CD195 (CCR5)

  • Brilliant Violet 421™ anti-human CD195 (CCR5)

  • FITC anti-human CD195 (CCR5)

  • Pacific Blue™ anti-human CD195 (CCR5)

  • PE/Dazzle™ 594 anti-human CD195 (CCR5)

  • APC anti-human CD195 (CCR5)

  • Brilliant Violet 510™ anti-human CD195 (CCR5)

  • Brilliant Violet 711™ anti-human CD195 (CCR5)

  • APC/Fire™ 750 anti-human CD195 (CCR5)

  • Brilliant Violet 785™ anti-human CD195 (CCR5)

  • TotalSeq™-A0141 anti-human CD195 (CCR5)

  • TotalSeq™-C0141 anti-human CD195 (CCR5)

  • TotalSeq™-B0141 anti-human CD195 (CCR5) Antibody

  • TotalSeq™-D0141 anti-human CD195 (CCR5)

  • PE/Cyanine5 anti-human CD195 (CCR5)

  • Brilliant Violet 605™ anti-human CD195 (CCR5)


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