APC anti-mouse IFN-γ R β chain Antibody

Pricing & Availability
MOB-47 (See other available formats)
Regulatory Status
Other Names
IFN-γ Receptor β chain, IFN-γ AF-1
Armenian Hamster IgG
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Product Citations
Murine lymphoma cell line A20 was stained with IFN-γR β chain (clone MOB-47) APC (filled histogram) or Armenian Hamster IgG APC isotype control (open histogram).
  • MOB-47_APC_IFN-yRB-Antibody_061918
    Murine lymphoma cell line A20 was stained with IFN-γR β chain (clone MOB-47) APC (filled histogram) or Armenian Hamster IgG APC isotype control (open histogram).
See APC spectral data
Cat # Size Price Quantity Check Availability Save
113605 25 µg £90
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113606 100 µg £195
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IFN-γ receptor β chain is also known as IFN-γ AF-1. This 60-65 kD class II cytokine receptor pairs with CDw119 to form the IFN-γ receptor. CDw119 serves as the IFN-γ-binding chain and associates with the IFN-γ β chain which is required for receptor signaling. The extracellular portion of both the IFN-γ receptor α and β chains must be species matched. The IFN-γ receptor β chain is expressed at low levels on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Armenian Hamster
Mouse IFN-γR β chain protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: Western blotting1 and immunoprecipitation1. For the most successful immunofluorescent staining results, it may be necessary to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 113604) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204)).

Application References

(PubMed link indicates BioLegend citation)
  1. Bach EA, et al. 1995. Science 270:1215.
Product Citations
  1. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
AB_2734170 (BioLegend Cat. No. 113605)
AB_2783052 (BioLegend Cat. No. 113606)

Antigen Details

Class II cytokine receptor family, associates with CDw119, 60-65 kD, AF-1

T and B cells, NK cells, monocytes, macrophages, granulocytes, fibroblasts

Regulates immune response, upregulates MHC class I expression
Cell Type
B cells, Fibroblasts, Granulocytes, Macrophages, Monocytes, NK cells, T cells
Biology Area
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References

1. Bach EA, et al. 1995. Science 270:1215. 
2. Ansel KM, et al. 2003. Nat. Immunol. 4:616.

Gene ID
15978 View all products for this Gene ID
View information about IFN-gamma R beta chain on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 06/19/2018

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • PE anti-mouse IFN-γR β chain

  • APC anti-mouse IFN-γ R β chain


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