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- Clone
- W17055E (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Human TGF-b Receptor II, TGFbRII
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with CD3 APC/Cyanine7 and TGF-β receptor II (clone W17055E) APC or rat IgG2b, κ APC isotype control.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 399705 | 25 tests | £99.00 | ||||
| 399706 | 100 tests | £202.00 | ||||
Transforming growth factor beta receptor 2 (TGFbR2 or TGFbRII) forms a heterodimeric complex on the cell surface with TGFbR1. TGFbR2 binds TGF-beta and is important for cell proliferation, wound healing, immunosuppression, and tumorigenesis.
Product DetailsProduct Details
- Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- TGFbR2 protein (aa 1-243) expressing transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- RRID
-
AB_2876726 (BioLegend Cat. No. 399705)
AB_2876726 (BioLegend Cat. No. 399706)
Antigen Details
- Distribution
-
B cells, T cells, monocytes, and granulocytes.
- Ligand/Receptor
- TGFbR2 forms a heterodimeric complex with TGFbR1 and binds TGF-β.
- Cell Type
- B cells, Monocytes, T cells
- Biology Area
- Immunology
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
- Horbelt D, et al. 2010. J Cell Sci. 123:4340-50.
- Wei CY, et al. 2015. Int J Clin Exp Pathol. 8:14619-29.
- Numata S, et al. 2008. J Psychiatr Res. 42:425-32.
- Gene ID
- 7048 View all products for this Gene ID
- UniProt
- View information about TGF-beta Receptor II on UniProt.org
Related Pages & Pathways
Pathways
Related FAQs
Other Formats
View All TGF-β Receptor II Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human TGF-β Receptor II | W17055E | FC |
| PE anti-human TGF-β Receptor II | W17055E | FC |
| APC anti-human TGF-β Receptor II | W17055E | FC |
| TotalSeq™-D1171 anti-human TGF-β Receptor II | W17055E | PG |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human TGF-β Receptor II
-
PE anti-human TGF-β Receptor II
-
APC anti-human TGF-β Receptor II
-
TotalSeq™-D1171 anti-human TGF-β Receptor II
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