APC anti-human CD48 Antibody

Pricing & Availability
Clone
BJ40 (See other available formats)
Other Names
Blast-1, SLAMF2, HuLy-m3
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
BJ40_APC_CD48_Antibody_051619.png
Human peripheral blood lymphocytes were stained with CD48 (clone BJ40) APC (filled histogram) or mouse IgG1, κ APC (open histogram).
  • BJ40_APC_CD48_Antibody_051619.png
    Human peripheral blood lymphocytes were stained with CD48 (clone BJ40) APC (filled histogram) or mouse IgG1, κ APC (open histogram).
See APC spectral data
Cat # Size Price Quantity Avail. Save
336713 25 tests £64
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336714 100 tests £114
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Description

CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human, African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation.

Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. 1997. Leucocyte Typing VI:White Cell Differentiation Antigens. Garland Publishing Inc.
  2. Wang R, et al. 2012. J. Leukoc Biol. 91:299. PubMed

Antigen Details

Structure
CD2 family, contains 2 IgSF domains, GPI-membrane anchored, 40-47 kD
Distribution

Widely expressed on hematopoietic cells except granulocytes, platelets, and erythrocytes. Increased on T and B cells after activation

Function
Contributes to T cell antigen recognition
Ligand/Receptor
CD2
Cell Targets
Lck, Fyn interact with cytoplasmic domain
Cell Type
B cells
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Fisher RC and Thorley-Lawson DA. 1991. Mol. Cell. Biol. 11:1614.
  2. Korinek V, et al. 1991. Immunogenetics 33:108.
  3. Leukocyte Typing IV. Knapp W, et al. (Eds) Oxford University Press (1989)
  4. Leukocyte Typing V. Schlossman S, et al. (Eds) Oxford University Press (1995)
Gene ID
962 View all products for this Gene ID
UniProt
View information about CD48 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 05/16/2019

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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