APC anti-human CD307e (FcRL5) Antibody

Pricing & Availability
509f6 (See other available formats)
Regulatory Status
Other Names
Mouse IgG2a, κ
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Product Citations
Human FcRL5 transfected P815 cell line was stained with CD307e (clone 509F6) APC (filled histogram) or mouse IgG2a, κ APC isotype control (open histogram).
  • 509F6_APC_CD307e_Antibody_FC_092514
    Human FcRL5 transfected P815 cell line was stained with CD307e (clone 509F6) APC (filled histogram) or mouse IgG2a, κ APC isotype control (open histogram).
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340305 25 tests £102
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340306 100 tests £256
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FcRL5, also known as CD307e, CD307, IRTA2, FcRH5, and BXMAS1, is a 106 kD type I transmembrane glycoprotein composed of six-eight extracellular Ig like C2 domains and two cytoplasmic ITIM motifs. The FcRL5 gene is located on chromosome 1q21 and is normally expressed by tonsillar plasma cells and germinal center B cells. It has been suggested that FcRL5 contributes to B cell maturation and B cell receptor modulation. The identification of FcRL5 on a number of transformed cell types including hairy cell leukemia, mantle cell lymphoma, chronic lymphocytic lymphoma, and Burkitt’s lymphoma has prompted interest in it as a potential biomarker or target for immunotherapy. FcRL5 binds all aggregated IgG isotypes.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
P815 cells transfected with FcRL5
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation and blocking1. mAb 509f6 is able to block the binding of FcRL5 to all aggregated IgG isotypes.1

Application References

(PubMed link indicates BioLegend citation)
  1. Wilson TJ, et al. 2012. J. Immunol. 188:4741. (Block)
Product Citations
  1. SoRelle ED, et al. 2022. Front Immunol. 13:1001145. PubMed
  2. Sutton HJ, et al. 2021. Cell Reports. 34(6):108684. PubMed
  3. Csomós K, et al. 2022. Nat Immunol. 23:1256. PubMed
  4. Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
AB_2564326 (BioLegend Cat. No. 340305)
AB_2564327 (BioLegend Cat. No. 340306)

Antigen Details

106 kD, Fc receptor like, type 1 transmembrane protein, 6-8 Ig like C2 domains, 2 cytoplasmic ITIM motifs.

Germinal center B cells, tonsillar plasma cells.

Aggregated IgG
Cell Type
B cells, Plasma cells
Biology Area
Molecular Family
CD Molecules
Antigen References

1. Davis R, et al. 2007. Annu. Rev. Immunol. 207:528.
2. Mohan J, et al. 2006. Blood 107:4433.
3. Ise T, et al. 2007. Leukemia. 21:169.

Gene ID
83416 View all products for this Gene ID
View information about CD307e on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 10/27/2014

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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  • TotalSeq™-B0829 anti-human CD307e (FcRL5) Antibody


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