- HM47 (See other available formats)
- Regulatory Status
- V cB017
- Other Names
- Mb-1, Iga, CD79
- Mouse IgG1, κ
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- Product Citations
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CD79a is a 47 kD type I integral membrane protein, also known as mb-1 or Iga. It is a member of the Ig superfamily and disulphide-associated with CD79b (B29). The interaction of CD79a/CD79b heterodimer with B cell suface Ig forms B cell antigen complex. CD79a is expressed in B cells from early pre-B to plasma cell stage. It has been shown that CD79a is also weakly expressed in some precursors of T- and myeloid cells. CD79 mediates the transport of IgM to B cell surface and transduces signals initiated by BCR aggregation.Product Details
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
ICFC - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. For immunohistochemistry on formalin-fixed paraffin-embedded tissue, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
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- Excitation Laser
Red Laser (633 nm)
AB_2734330 (BioLegend Cat. No. 333515)
AB_2734331 (BioLegend Cat. No. 333516)
- 47 kD, type I integral protein, Ig superfamily, CD79a/CD79b heterodimer interacts with B cell membrane Ig.
B cells (from early pre-B to plasma cell stage), some T and myeloid cell precursors
- In association with CD79b and B cell membrane Ig to form B cell antigen receptor complex
- Cell Type
- B cells, Hematopoietic stem and progenitors
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Zola Heddy, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD markers. WILEY-LISS
2. Astsaturov IA, et al. 1996. Leukemia 10:769
3. Mson DY, et al. 1995 Blood 86:1453
4. Hashimoto M, et al. 2002. J. Pathol. 197:341
- Gene ID
- 973 View all products for this Gene ID
- View information about CD79a on UniProt.org
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