Adhesion Molecules

Cell adhesion molecules (CAMs) mediate cell-to-cell and/or cell-to-extracellular matrix (ECM) interactions. In general, the CAMs belong to four different families: immunoglobulin (Ig) superfamily, integrins, cadherins, and selectins. Interactions mediated by CAMs can be either adhesive or inhibitory in nature. These interactions can also be associated with changes in downstream signaling pathways, cytoskeletal reorganization, or gene expression.

Featured Data

Recombinant Human CD6 (Carrier-Free)

 

 

Human CD6 was aliquoted in 20 mM Tris, 150 mM NaCl, pH 7.2 at 0.2 mg/ml. One aliquot was frozen and thawed four times (4x freeze/thaws) and another aliquot was kept at 37°C for one week. The proteins were tested for their ability to support the adhesion of Jurkat cells compared to a control kept at 4°C.

Recombinant Human ALCAM/CD166 (Carrier-Free)

 

 

Human ALCAM was aliquoted in 20mM Tris, 150mM NaCl, pH 7.2 at 0.2 mg/ml. One aliquot was frozen and thawed four times and another aliquot was kept at 37°C for one week. The proteins were tested for their ability to block adhesion of Jurkat cells to immobilized human CD6 compared to a control kept at 4°C.