Purified anti-mouse IL-17RB Antibody

Pricing & Availability
9B10 (See other available formats)
Regulatory Status
Other Names
Evi27, IL-17ER, IL17RH1, IL17br, IL-17 receptor B
Rat IgG2a, κ
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Product Citations
Mouse IL-17RB transfected 300.19 cells were stained with purified IL-17RB (clone 9B10, filled histogram) or rat IgG2a, κ (open histogram), followed by anti-rat IgG PE.
  • 9B10_Purified_IL-17RB_Antibody_FC_080113
    Mouse IL-17RB transfected 300.19 cells were stained with purified IL-17RB (clone 9B10, filled histogram) or rat IgG2a, κ (open histogram), followed by anti-rat IgG PE.
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146302 100 µg 199€
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IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family.  IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R.  It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells.  It binds IL-17B and IL-17E (IL-25) but not IL-17A or C.  Its interaction with IL-25 has a higher affinity than that with IL-17B.  Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1.  IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Recombinant mouse IL-17RB - Fc chimera (human IgG1)
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

AB_2562379 (BioLegend Cat. No. 146302)

Antigen Details

Single pass type I transmembrane protein, 55.9 kD
iNKT cells, innate lymphoid cells, Th2 cells
Binds IL-25 with higher affinity than IL-17B, can block IL-25 mediated pathology
TRAF6 and Act1
Cell Type
NKT cells, Th2
Biology Area
Immunology, Innate Immunity
Molecular Family
Cytokine/Chemokine Receptors
Antigen References

1. Hwang SY, et al. 2004. Arthritis Res. Ther. 6:R120.
2. Rickel EA, et al. 2008. J. Immunol. 181:4299.
3. Terashima A, et al. 2008. J. Exp. Med. 205:2727.

Gene ID
50905 View all products for this Gene ID
View information about IL-17RB on UniProt.org

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Go To Top Version: 2    Revision Date: 09.23.2013

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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