Purified anti-mouse CD339 (Jagged 1) Antibody

Pricing & Availability
HMJ1-29 (See other available formats)
Regulatory Status
Other Names
JAG1, Jagged1
Armenian Hamster IgG
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Product Citations
Mouse Jagged 1 transfected CHO cells were stained with purified HMJ1-29 (filed histogram) or purified Armenian hamster IgG isotype control (open histogram), followed by anti-hamster IgG PE.
  • HMJ1-29_Purified_HMJ1-29_Antibody_FC_072313
    Mouse Jagged 1 transfected CHO cells were stained with purified HMJ1-29 (filed histogram) or purified Armenian hamster IgG isotype control (open histogram), followed by anti-hamster IgG PE.
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130902 500 µg 259€
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CD339, also known as Jagged 1, is a 135 kD type 1 transmembrane protein, with one DSL (Delta, Serrate, LagZ) domain, fifteen EGF-like domains, and one cysteine-rich region. Jagged 1 is expressed by many cell types including macrophages, subsets of dendritic cells, astrocytes, stromal, and epithelial cells. CD339 regulates cell fate decisions in various tissues, and has an important role in neurogenesis and development of the cardiovascular system. Studies suggest Jagged 1 is involved in Th2 polarization and Treg induction.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
Armenian Hamster
Murine Jagged 1-Fc fusion protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IHC-F - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: in vivo blocking of Jagged 1 in EAE1 and immunohistochemical staining of frozen spleen sections2.

Application References

(PubMed link indicates BioLegend citation)
  1. Elyaman W, et al. 2007. J. Immunol. 179:5990. (Block)
  2. Sekine C, et al. 2009. Int. Immunol. 21:295. (IHC)
Product Citations
  1. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  2. Martinez-Lozada Z, et al. 2020. Neurochemistry International. 139:104787. PubMed
  3. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  4. Sharma VP, et al. 2021. Nat Commun. 12:7300. PubMed
AB_2561301 (BioLegend Cat. No. 130902)

Antigen Details

Type 1 transmembrane protein, 1 DSL (Delta, Serrate, LagZ) domain, 15 EGF-like domains, 1 cystein riche region; 135 kD

Macrophages, subsets of dendritic cells, stromal cells, epithelial cells, astrocytes

Regulates cell fate decisions in various tissues, important role in cardiovascular system development, neurogenesis, and T cell polarization to Th2 lineage
Notch1, Notch2, Notch3
Cell Type
Astrocytes, Dendritic cells, Epithelial cells, Macrophages
Biology Area
Angiogenesis, Cell Biology, Immunology
Molecular Family
CD Molecules
Antigen References

1. Amsen D, et al. 2004. Cell. 117:515.
2. Cheng P, et al. 2007. Blood. 109: 507. 
3. Goh F, et al. 2009. Immunology. 127:326. 
4. Zeng H, et al. 2012. PLoS One. 7:e35905.

Gene ID
16449 View all products for this Gene ID
View information about CD339 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 08.28.2013

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This data display is provided for general comparisons between formats.
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