Loading...

Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
Ave. Rating
Submit a Review
Product Citations
publications
93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
Compare all formats
Cat # Size Price Quantity Check Availability Save
101301 50 µg 29€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
101302 500 µg 92€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References

(PubMed link indicates BioLegend citation)
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  2. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  3. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  4. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  5. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  6. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  7. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  8. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  9. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  10. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  11. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  12. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  13. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  14. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  15. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  16. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  17. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  18. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  19. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  20. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  21. Barkaway A, et al. 2021. Immunity. . PubMed
  22. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  23. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  24. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  25. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  26. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  27. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  28. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  29. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  30. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  31. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  32. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  33. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  34. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  35. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  36. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  37. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  38. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  39. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  40. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  41. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  42. Mevel R, et al. 2020. eLife. 9:00. PubMed
  43. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  44. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  45. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  46. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  47. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  48. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  49. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  50. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  51. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  52. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  53. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  54. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  55. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  56. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  57. Feng J, et al. 2021. iScience. 24:103004. PubMed
  58. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  59. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  60. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  61. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  62. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  63. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  64. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  65. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  66. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  67. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  68. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  69. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  70. Goel S, et al. 2017. Nature. 548:471. PubMed
  71. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  72. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  73. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  74. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  75. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  76. Diao L, et al. 2022. iScience. 25:105511. PubMed
  77. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  78. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  79. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  80. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  81. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  82. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  83. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  84. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  85. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  86. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  87. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  88. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  89. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  90. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  91. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  92. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  93. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  94. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  95. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  96. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  97. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  98. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  99. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  100. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  101. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  102. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  103. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  104. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  105. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  106. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  107. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  108. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  109. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  110. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  111. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  112. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  113. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  114. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  115. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  116. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  117. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  118. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  119. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  120. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  121. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  122. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  123. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  124. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  125. Tal MC, et al. 2020. MBio. 11:00. PubMed
  126. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  127. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  128. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  129. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  130. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  131. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  132. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  133. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  134. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  135. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  136. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  137. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  138. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  139. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  140. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  141. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  142. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  143. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  144. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  145. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  146. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  147. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  148. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  149. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  150. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  151. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  152. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  153. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  154. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  155. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  156. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  157. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  158. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  159. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  160. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  161. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  162. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  163. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  164. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  165. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  166. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  167. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  168. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  169. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  170. Wong HS, et al. 2021. Cell. . PubMed
  171. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  172. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  173. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  174. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  175. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  176. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  177. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  178. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  179. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  180. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  181. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  182. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  183. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  184. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  185. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  186. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  187. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  188. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  189. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  190. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  191. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  192. Baasch S, et al. 2021. Cell. . PubMed
  193. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  194. Zheng J, et al. 2020. bioRxiv. . PubMed
  195. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  196. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  197. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  198. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  199. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  200. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  201. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  202. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  203. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  204. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  205. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  206. Welte T, et al. 2021. iScience. 24:103349. PubMed
  207. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  208. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  209. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  210. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  211. Xu S, et al. 2021. Immunity. . PubMed
  212. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  213. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  214. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  215. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  216. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  217. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  218. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  219. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  220. Roy K, et al. 2019. Immunity. 50:616. PubMed
  221. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  222. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  223. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  224. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  225. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  226. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  227. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  228. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  229. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  230. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  231. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  232. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  233. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  234. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  235. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  236. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  237. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  238. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  239. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  240. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  241. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  242. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  243. Zheng J, et al. 2020. Nature. . PubMed
  244. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  245. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  246. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  247. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  248. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  249. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  250. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  251. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  252. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  253. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  254. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  255. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  256. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  257. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  258. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  259. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  260. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  261. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  262. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  263. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  264. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  265. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  266. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  267. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  268. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  269. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  270. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  271. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  272. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  273. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  274. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  275. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  276. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  277. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  278. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  279. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  280. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  281. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  282. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  283. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  284. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  285. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  286. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  287. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  288. Lenert R 2005. J Immunol. 174:2429. PubMed
  289. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  290. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  291. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  292. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  293. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  294. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  295. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  296. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  297. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  298. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  299. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  300. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  301. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  302. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  303. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  304. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  305. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  306. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  307. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  308. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  309. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  310. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  311. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  312. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  313. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  314. Lee SA, et al. 2021. Cells. 10:. PubMed
  315. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  316. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  317. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  318. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  319. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  320. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  321. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  322. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  323. William M, et al. 2018. J Immunol. 200:4102. PubMed
  324. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  325. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  326. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  327. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  328. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  329. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  330. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  331. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  332. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  333. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  334. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  335. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  336. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  337. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  338. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  339. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  340. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  341. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  342. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  343. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  344. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  345. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  346. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  347. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  348. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  349. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  350. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  351. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  352. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  353. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  354. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  355. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  356. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  357. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  358. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  359. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  360. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  361. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  362. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  363. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  364. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  365. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  366. Sibler E, et al. 2021. Cells. 10:. PubMed
  367. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  368. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  369. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  370. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  371. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  372. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  373. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  374. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  375. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  376. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  377. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  378. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  379. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  380. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  381. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  382. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  383. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  384. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  385. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  386. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  387. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  388. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312801 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org
Go To Top Version: 2    Revision Date: 01.23.2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account