- NK92.39 (See other available formats)
- Other Names
- Tactile (T cell-activated increased late expression)
- Mouse IgG1, κ
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- Product Citations
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CD96, known as TACTILE (T cell-activated increased late expression), is a 160 kD type I transmembrane glycoprotein and is a member of the Ig superfamily molecules. It is expressed on NK cells, T cells (up-regulated upon activation), and some acute myeloid leukemia (AML) cells, but not on normal B and myeloid cells. A soluble form of CD96 has been found in serum. CD96 is involved in T- and NK-cell adhesion through interaction with its ligand, CD155 (polio virus receptor).Product Details
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
FA - Reported in literature
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications include: block interaction of CD96 with PVR and functional assay
(PubMed link indicates BioLegend citation)
- Fuchs A, et al. 2004. J. Immunol. 172:3994
- Manes TD, et al. 2011. J. Immunol. 186:1763. PubMed
- Product Citations
AB_1279386 (BioLegend Cat. No. 338402)
- 160 kD, type I transmembrane protein, Ig superfamily
NK cells, T cells (upregulated upon activation)
- CD155 (PVR)
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity, Inhibitory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Hosen N, et al. 2007. Proc. Natl. Acad. Sci. USA 104:11008
3. Gong J, et al. 2008. Clin. Exp. Immunol.
- Gene ID
- 10225 View all products for this Gene ID
- View information about CD96 on UniProt.org
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