Purified anti-human CD70 Antibody

Pricing & Availability
113-16 (See other available formats)
Regulatory Status
Other Names
CD27 ligand, CD27L, Ki-24 antigen, Tumor necrosis factor ligand superfamily, member 7 (TNFSF7)
Mouse IgG1, κ
Ave. Rating
Submit a Review
Product Citations
Human myeloma cell line, U266, was stained with purified CD70 (clone 113-16, filled histogram) or mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
  • 113-16_Pure_070212
    Human myeloma cell line, U266, was stained with purified CD70 (clone 113-16, filled histogram) or mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
Compare all formats
Cat # Size Price Quantity Check Availability Save
355101 25 µg 52€
Check Availability

Need larger quantities of this item?
Request Bulk Quote
355102 100 µg 109€
Check Availability

Need larger quantities of this item?
Request Bulk Quote

CD70, also known as CD27L, is a 50 kD type II transmembrane glycoprotein and member of the tumor necrosis factor superfamily. CD70 is expressed on activated T, B and NK cells, activated plasmacytoid dendritic cells (pDCs), and chronic B cell lymphocytic leukemia and large B cell lymphomas. CD70 costimulates T cell proliferation and differentiation. It plays a role in the pDC-induced B cell differentiation. The ligand of CD70 is CD27.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Antibody Type
Host Species
CD70-transfected L cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications for the relevant formats include: blocking of plasmacytoid dendritic cell induced B cell proliferation and Ig secretion1.

Application References

(PubMed link indicates BioLegend citation)
  1. Shaw J, et al. 2010. Blood 115:3051. (Block)
Product Citations
  1. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  2. Tian Y, et al. 2019. Cell Rep. 29:4482. PubMed
  3. Francescone R, et al. 2020. Cancer Discovery. 11(2):446-479. PubMed
  4. Abolhassani H, et al. 2017. J Exp Med . 214(1):91-106. PubMed
  5. Ravell JC, et al. 2020. J Clin Invest. 130:507. PubMed
  6. Martin E, et al. 2020. JCI Insight. :5. PubMed
AB_2561428 (BioLegend Cat. No. 355101)
AB_2561429 (BioLegend Cat. No. 355102)

Antigen Details

Type II transmembrane glycoprotein, member of the tumor necrosis factor superfamily, 50 kD

Activated T cells and B cells, activated NK cells, activated plasmacytoid dendritic cells, some B cell lymphomas

Role in T cell proliferation, generation of cytolytic and memory T cells, B cell proliferation and differentiation
Cell Type
B cells, Dendritic cells, NK cells, T cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Bowman MR, et al. 1994. J. Immunol. 152:1756.
2. Shaw J, et al. 2010. Blood 115:3051.
3. Keller AM, et al. 2009. Blood 113:5167.

Gene ID
970 View all products for this Gene ID
View information about CD70 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 06.15.2022

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human CD70

  • PE anti-human CD70

  • FITC anti-human CD70

  • PerCP/Cyanine5.5 anti-human CD70

  • APC anti-human CD70

  • Alexa Fluor® 647 anti-human CD70

  • PE/Cyanine7 anti-human CD70

  • Biotin anti-human CD70

  • TotalSeq™-A0027 anti-human CD70

  • TotalSeq™-C0027 anti-human CD70

  • APC/Fire™ 750 anti-human CD70

  • PE/Dazzle™ 594 anti-human CD70

  • TotalSeq™-B0027 anti-human CD70

  • TotalSeq™-D0027 anti-human CD70


Login / Register
Remember me
Forgot your password? Reset password?
Create an Account