Purified anti-human CD159a (NKG2A) Antibody

Pricing & Availability
S19004C (See other available formats)
Regulatory Status
Other Names
Killer Cell Lectin Like Receptor C1, KLRC1, NK Cell Receptor A
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes were stained with purified CD159a (NKG2A) (clone S19004C) (left) or purified mouse IgG1, κ isotype ctrl (right), followed by anti-mouse IgG PE and CD3 Pacific Blue™.
  • S19004C_PURE_CD159a_Antibody_1_041620
    Human peripheral blood lymphocytes were stained with purified CD159a (NKG2A) (clone S19004C) (left) or purified mouse IgG1, κ isotype ctrl (right), followed by anti-mouse IgG PE and CD3 Pacific Blue™.
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375102 100 µg 264€
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CD159a, also known as NKG2A or KLRC1, is a type II transmembrane protein. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and T cell subsets. NKG2A is an inhibitory NK cell receptor and it is expressed as a heterodimer with CD94. In human, NKG2A/CD94 complex interacts HLA-E on target cells and inhibits T cells and NK cell effector functions. Recent studies showed that NKG2A blockade enhances the anti-tumor effect of NK cell and CD8+ T cells.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Human NKG2A/CD94-transfectants
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
The antibody was purified by affinity chromatography.
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone S19004C does not cross-react with mouse CD159a.

AB_2888860 (BioLegend Cat. No. 375102)

Antigen Details

Type II transmembrane proteins of the C-type lectin superfamily

NK cells, NKT cells, T cell subsets

Inhibiting NK cell receptor
Cell Type
Lymphocytes, NK cells, NKT cells, T cells
Biology Area
Immuno-Oncology, Immunology
Molecular Family
Immune Checkpoint Receptors
Antigen References
  1. Brooks AG, et al. 1999. J Immunol. 162:305-13.
  2. Kaiser BK, et al. 2008. Proc Natl Acad Sci U S A. 105: 6696-701.
  3. Braud VM, et al. 2003. Trends Immunol. 24:162-4.
  4. Kamiya T, et al. 2019. J Clin Invest. 129:2094.
  5. André P, et al. 2018. Cell. 175:1731.
Gene ID
3821 View all products for this Gene ID
View information about CD159a on UniProt.org

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Go To Top Version: 1    Revision Date: 04.16.2020

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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  • Biotin anti-human CD159a (NKG2A) Antibody

  • Alexa Fluor® 488 anti-human CD159a (NKG2A)

  • PerCP/Cyanine5.5 anti-human CD159a (NKG2A)


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