- AC11.AE12 (See other available formats)
- Other Names
- HIV TAT
Covance Catalog# MMS-116P
- Mouse IgG1
- Ave. Rating
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- Product Citations
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The HIV-1 TAT (transactivator of transcription) gene codes for a 14 kD protein and is vital for HIV-1 transcription. After infection, TAT is one of the first proteins expressed after HIV has taken over the host’s machinery. TAT is a RNA binding protein that recognizes the TAR (Transactivator Response Element) sequence found in the HIV-1 RNA molecule. It is also needed for the recruitment of the host positive transcription elongation factor b (p-TEFb). In neuron cells, TAT has been linked to progressive neuronal deregulation, HIV-Associated Neurocognitive Disorders and accelerating brain aging.Product Details
- 1-37 aa of HIV TAT Tag
- Antibody Type
- Host Species
- This antibody was generated against full-length HIV TAT protein.
- Phosphate-buffered solution + 0.03% Thimerosal.
- The antibody was purified by affinity chromatography.
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting.
The optimal working dilution should be determined for each specific assay condition.
• WB: 1:1,000*
- Application Notes
This antibody is effective in immunoblotting (WB).
*Predicted MW = 11 kD
The epitope is contained in the first 37 amino acids of the protein.
- Product Citations
AB_2565207 (BioLegend Cat. No. 919001)
- Biology Area
- Bacterial proteins and Toxins, Cell Biology
- Gene ID
- View information about HIV TAT on UniProt.org
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