Purified anti-HIV gp120 Antibody (Previously Covance catalog# MMS-193P)

Pricing & Availability
Clone
ED8.D4 (See other available formats)
Other Names
HTLV-III gp120, Envelope Glycoprotein gp120, HIV, gp120(HIV), HIV Envelope Glycoprotein gp120, HTLV III gp120, env Protein gp120, HIV, gp120 Envelope Glycoprotein, HIV, gp120, HTLV-III
Previously
Covance Catalog# MMS-193P
Isotype
Mouse IgG1
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Product Citations
publications
Cat # Size Price Quantity Avail. Save
906801 250 µl 240€
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Description

Glycoprotein 120, or gp120, is a human immunodeficiency virus (HIV) envelope protein derived from the proteolytic cleavage of gp160. It attaches HIV to host lymphoid cells by binding to the primary receptor CD4. This binding interaction induces a structural rearrangement creating another high affinity binding site for a chemokine co-receptor like CXCR4 and/or CCR5. The protein also serves as a ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR. CD209 in particular is an important interaction as dendritic cells loaded with viral particles can migrate to lymph nodes to provide access to T cells for infection.

Product Details
Technical data sheet

Product Details

Reactivity
HIV-1
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was raised against a peptide corresponding to the amino acid sequence 427-448 of the gp120 protein.
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB, ELISA

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting.

The optimal working dilution should be determined for each specific assay condition.
WB: 1:500*
ELISA: 1:500
 

Application Notes

This antibody is effective in immunoblotting and ELISA.

*Predicted MW = 120 kD

Application References

(PubMed link indicates BioLegend citation)
  1. Not Published
RRID
AB_2565069 (BioLegend Cat. No. 906801)

Antigen Details

Biology Area
Bacterial proteins and Toxins, Cell Biology, Signal Transduction
Gene ID
155971 View all products for this Gene ID
UniProt
View information about HIV gp120 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 3    Revision Date: 07.20.2016

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

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