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PE anti-human Ksp37 (FGFBP2) Antibody

Pricing & Availability
Clone
TDA3 (See other available formats)
Regulatory Status
RUO
Other Names
Killer-specific secretory protein of 37 kD (Ksp37), FGF binding protein 2 (FGFBP2), Fibroblast growth factor binding protein 2
Isotype
Mouse IgG1, κ
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Product Citations
publications
A_TDA3_PE_011310
Human peripheral blood lymphocytes surface stained with CD56 APC then intracellularly stained with TDA3 PE
  • A_TDA3_PE_011310
    Human peripheral blood lymphocytes surface stained with CD56 APC then intracellularly stained with TDA3 PE
  • B_TDA3_PE_011310
    Human peripheral blood lymphocytes surface stained with CD3 FITC and then intracellularly stained with Ksp37 (TDA3) PE
See PE spectral data
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346603 25 tests 117€
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Description

Ksp37 (killer-specific secretory protein of 37 kD), also known as FGFBP2 (FGF binding protein 2), is a 37 kD Th1-specific secretory protein. It is produced by NK cells, γ/δ T cells, a subset of effector CD8 T cells and Th1 cells, and secreted to serum. Most Ksp37 expressing cells coexpress perforin. It suggests that Ksp37 may be involved in an essential process of cytotoxic lymphocyte-mediated immunity. Elevated Ksp37 level in body fluids has been found in asthma and some infectious disease patients.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Ksp37 cDNA and recombinant Ksp37
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

This product is sold under license agreement with BML, Inc for research use only.

Application References

(PubMed link indicates BioLegend citation)
  1. Ogawa K, et al. 2001. J. Immunol. 166:6404
  2. Kuepper M, et al. 2004. Clin. Exp. Immunol. 137:359
Product Citations
  1. de Andrade LF, et al. 2019. JCI Insight. 4:e133103. PubMed
  2. Yeo L, et al. 2018. J Clin Invest. 128:3460. PubMed
  3. Collins PL et al. 2018. Cell. 176(1-2):348-360 . PubMed
  4. Corrales L, et al. 2012. J Immunol. 189:4674. PubMed
RRID
AB_2103097 (BioLegend Cat. No. 346603)

Antigen Details

Structure
FGF binding protein family, secreted to serum, 37 kD
Distribution
NK cells, γ/δ T cells, subset of effector CD8 T cells and Th1 cells
Cell Type
NK cells, T cells, Th1
Biology Area
Immunology, Innate Immunity
Antigen References

1. Kuepper M, et al. 2005. Clin. Exp. Allergy. 35:643
2. Kuepper M, et al. 2004. Clin. Exp. Immunol. 137:359

Gene ID
643236 View all products for this Gene ID
UniProt
View information about Ksp37 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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  • PE anti-human Ksp37 (FGFBP2)
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