- Clone
- 63D3 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein, LPS receptor
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications

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Human peripheral blood monocytes were stained with biotinylated anti-human CD14 (clone 63D3) (filled histogram) or biotinylated mouse IgG1, κ (open histogram), followed by SAV-PE.
Cat # | Size | Price | Quantity Check Availability | Save | ||
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367105 | 25 µg | 72€ | ||||
367106 | 100 µg | 165€ |
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein that is also known as the LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Purified human peripheral blood monocytes.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Fridlender ZG, et al. 1999. Hum. Immunol. 11:1028.
- Devitt A, et al. 1998. Nature 6675:505.
- Product Citations
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- RRID
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AB_2566617 (BioLegend Cat. No. 367105)
AB_2566618 (BioLegend Cat. No. 367106)
Antigen Details
- Structure
- GPI-linked membrane glycoprotein.
- Distribution
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Monocytes, macrophages, dendritic cells, and granulocytes.
- Function
- LPS receptor, clearance of Gram-negative pathogens.
- Interaction
- LPS.
- Ligand/Receptor
- LPS.
- Cell Type
- Dendritic cells, Granulocytes, Macrophages, Monocytes, Neutrophils
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
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- Stocks SC, et al. 1990. Biochem. J. 268:275.
- Wright SD, et al. 1990. Science 4975:1431.
- Gene ID
- 929 View all products for this Gene ID
- UniProt
- View information about CD14 on UniProt.org
Related FAQs
- How many biotin molecules are per antibody structure?
- We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Other Formats
View All CD14 Reagents Request Custom ConjugationCustomers Also Purchased



Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD14
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PE anti-human CD14
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Biotin anti-human CD14
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APC/Cyanine7 anti-human CD14
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PE/Cyanine7 anti-human CD14
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PerCP/Cyanine5.5 anti-human CD14
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Alexa Fluor® 700 anti-human CD14
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APC anti-human CD14
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FITC anti-human CD14
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APC/Fire™ 750 anti-human CD14
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Pacific Blue™ anti-human CD14
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Brilliant Violet 510™ anti-human CD14
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Brilliant Violet 605™ anti-human CD14
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Alexa Fluor® 647 anti-human CD14
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Alexa Fluor® 488 anti-human CD14
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TotalSeq™-A0051 anti-human CD14
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PE/Dazzle™ 594 anti-human CD14
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Brilliant Violet 750™ anti-human CD14
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TotalSeq™-C0051 anti-human CD14
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Brilliant Violet 421™ anti-human CD14
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Brilliant Violet 785™ anti-human CD14
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Brilliant Violet 711™ anti-human CD14
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TotalSeq™-B0051 anti-human CD14
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Spark Blue™ 550 anti-human CD14
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Spark NIR™ 685 anti-human CD14
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PE/Fire™ 640 anti-human CD14
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APC/Fire™ 810 anti-human CD14
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PerCP anti-human CD14
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PE/Fire™ 700 anti-human CD14
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