- 4B2.9 (See other available formats)
- Regulatory Status
- Other Names
- Vγ1 and Vγ2 (Tonegawa nomenclature)
- Armenian hamster IgG
- Ave. Rating
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- Product Citations
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In mice, the TCR g locus consists of seven Vg, four Jg and four Cg genes, which are differentially expressed through their lifespan. During fetal and early postnatal life, very few γ/δ T cells express TCR Vγ1.1 or Vγ1.2 chains. In adult mice, however, a major fraction of the γ/δ T cell repertoire comprise either TCR Vγ1.1 or Vγ1.2 chains. The Vγ1.1 gene rearranges almost exclusively with the Jg4-Cg4 genes, while the Vγ1.2 gene preferentially does with Jg1.Product Details
- Antibody Type
- Host Species
- Armenian Hamster
- TCR Vγ1.1/Vδ6 T3.13.1 hybridoma
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
mAb 4B2.9 specifically recognizes γ/δ T cells expressing Vγ1.1 and/or Vγ1.2 chains.
(PubMed link indicates BioLegend citation)
- Pereira P and Boucontet L. 2004. J. Immunol. 173:3261. (FC)
AB_10960122 (BioLegend Cat. No. 142702)
- Subset of γ/δ T cells
- Antigen recognition
- Cell Type
- T cells
- Biology Area
- Immunology, Adaptive Immunity
- Molecular Family
- Antigen References
1. Garcia-Herrera A, et al. 2011. Am. J. Surg. Pathol. 35:1214.
2. Gutierrez A, et al. 2010. J. Clin. Oncol. 28:3816.
3. Zhang X, et al. 2009. Hematology 14:237.
- Gene ID
- 110067 View all products for this Gene ID
- View information about TCR Vg1.1 + Vg1.2 on UniProt.org
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