Purified anti-mouse CD209a (DC-SIGN) Antibody (Previously Covance catalog# MMS-5224)

Pricing & Availability
Clone
MMD3 (See other available formats)
Regulatory Status
RUO
Other Names
CD209 antigen-like protein A, dendritic cell-specific ICAM-3-grabbing non-integrin, CIRE, CD209, CDSIGN
Previously
Covance Catalog# MMS-5224
Isotype
Mouse IgG2c
Ave. Rating
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Product Citations
publications
MMD3_Purified_CD209a_Antibody_FC_081017_updated
CHO-DC-SIGN transfected (filled histogram) & CHO-K1 (dashed histogram) cell lines were stained with Purified anti-mouse CD209a (clone MMD3) antibody, followed by PE anti-mouse IgG2a antibody (clone RMG2a-62).
  • MMD3_Purified_CD209a_Antibody_FC_081017_updated
    CHO-DC-SIGN transfected (filled histogram) & CHO-K1 (dashed histogram) cell lines were stained with Purified anti-mouse CD209a (clone MMD3) antibody, followed by PE anti-mouse IgG2a antibody (clone RMG2a-62).
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833001 100 µL 187,00€
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Description

CD209a, is also known as Dendritic Cell-Specific Intercellular adhesion molecule 3 (ICAM-3)-Grabbing Nonintegrin (DC-SIGN) and CIRE. CD209a is the mouse homolog of human CD209, and is expressed on myeloid dendritic cells, placental macrophages, liver and placental endothelial cells. CD209 binds to ICAM-3 (CD50), ICAM-2 (CD102), and Butyrophilin (BTN2A1), and mediates dendritic cell migration and T cell proliferation. It plays a critical role in capturing and internalizing pathogens such as Streptococcus pneumoniae.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against a purified extracellular domain of mouse CD209a (DC-SIGN)-IgG1 Fc fusion protein.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

FC

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis.

The optimal working dilution should be determined for each specific assay condition.
FC: 1 μg/test

Application Notes

This antibody is effective in Flow Cytometry (FC).

FC Positive Control: Mouse splenocytes

Product Citations
  1. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
RRID
AB_2564962 (BioLegend Cat. No. 833001)

Antigen Details

Biology Area
Cell Biology, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Gene ID
170786 View all products for this Gene ID
UniProt
View information about CD209a on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 07.13.2016

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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