Purified anti-human HLA-DR Recombinant Antibody

Pricing & Availability
Clone
QA19A44 (See other available formats)
Regulatory Status
RUO
Other Names
Major Histocompatibility Class II, MHC class II
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA19A15_PURE_HLA-DR_RECOM_Antibody_091021.png
Human peripheral blood lymphocytes were stained with CD20 PE and HLA-DR (clone QA19A44) purified (left) or purified mouse IgG1, κ isotype control (right) followed by anti-mouse IgG APC.
  • QA19A15_PURE_HLA-DR_RECOM_Antibody_091021.png
    Human peripheral blood lymphocytes were stained with CD20 PE and HLA-DR (clone QA19A44) purified (left) or purified mouse IgG1, κ isotype control (right) followed by anti-mouse IgG APC.
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365602 100 µg 88,00€
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Description

HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2894694 (BioLegend Cat. No. 365602)

Antigen Details

Structure
Ig superfamily, MHC class II, heterodimeric transmembrane protein, 36 kD heavy and 27 kD light chain
Distribution

B cells, activated T cells, monocytes/macrophages, dendritic cells, other APCs

Function
Peptide presentation
Ligand/Receptor
CD3/TCR, CD4
Cell Type
Antigen-presenting cells, B cells, Dendritic cells, Macrophages, Monocytes, T cells, Tregs
Biology Area
Immunology, Innate Immunity
Molecular Family
MHC Antigens
Antigen References
  1. Levacher M, et al. 1990. Clin Exp Immunol. 81:177.
  2. Terstappen L, et al. 1990. J Leukocyte Biol. 48:138.
  3. Edwards JA, et al. 1986. J Immunol. 137:490.
  4. van Es A, et al. 1984. Transplantation. 37:65.
  5. O'Doherty U, et al. 1994. Immunology. 82:487.
  6. Thomas R, et al. 1994. J Immunol. 153:4016.
  7. Grouard G, et al. 1996. Nature. 384:364.
Gene ID
3122 View all products for this Gene ID 3123 View all products for this Gene ID
UniProt
View information about HLA-DR on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 09.10.2021

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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