- 201A (See other available formats)
- Regulatory Status
- Other Names
- CLEC4C, CLECSF11, CLECSF7, DLEC, HECL
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
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CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.Product Details
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.
- The antibody was purified by affinity chromatography.
- 1.0 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
CyTOF® - Verified
- Recommended Usage
This product is suitable for use with the Maxpar® Metal Labeling Kits. The product is formulated to simplify the antibody preparation when performing the labeling protocol. As a result, it is possible to proceed directly to the step to Partially Reduce the Antibody by adding 100 µl of Maxpar® Ready antibody to 100 µl of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar® User Guide when conjugating Maxpar® Ready antibodies.
- Additional Product Notes
Maxpar® is a registered trademark of Fluidigm Inc.
(PubMed link indicates BioLegend citation)
- Product Citations
AB_2563739 (BioLegend Cat. No. 354215)
- Type II transmembrane protein, 38 kD, member of the C-type lectin superfamily
Plasmacytoid dendritic cells
- Antigen capture, inhibition of IFN α/β production
- Cell Type
- Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
1. Jähn PS, et al. 2010. Cell Immunol. 265:15.
2. Graham LM and Brown GD. 2009. Cytokine 48:148.
3. Röck J, et al. 2007. Eur. J. Immunol. 37:3564.
4. Dzionek A, et al. 2001. J. Exp. Med. 194:1823.
- Gene ID
- 170482 View all products for this Gene ID
- View information about CD303 on UniProt.org
- Can I obtain CyTOF data related to your Maxpar® Ready antibody clones?
We do not test our antibodies by mass cytometry or on a CyTOF machine in-house. The data displayed on our website is provided by Fluidigm®. Please contact Fluidigm® directly for additional data and further details.
- Can I use Maxpar® Ready format clones for flow cytometry staining?
We have not tested the Maxpar® Ready antibodies formulated in solution containing EDTA for flow cytometry staining. While it is likely that this will work in majority of the situations, it is best to use the non-EDTA formulated version of the same clone for flow cytometry testing. The presence of EDTA in some situations might negatively affect staining.
- I am having difficulty observing a signal after conjugating a metal tag to your Maxpar® antibody. Please help troubleshoot.
We only supply the antibody and not test that in house. Please contact Fluidigm® directly for troubleshooting advice: http://techsupport.fluidigm.com/
- Is there a difference between buffer formulations related to Maxpar® Ready and purified format antibodies?
The Maxpar® Ready format antibody clones are formulated in Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA. The regular purified format clones are formulated in solution that does not contain any EDTA. Both formulations are however without any extra carrier proteins.
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
APC anti-human CD303 (BDCA-2)
Biotin anti-human CD303 (BDCA-2)
Brilliant Violet 785™ anti-human CD303 (BDCA-2)
Brilliant Violet 605™ anti-human CD303 (BDCA-2)
TotalSeq™-C0370 anti-human CD303 (BDCA-2)
FITC anti-human CD303 (BDCA-2)
PerCP/Cyanine5.5 anti-human CD303 (BDCA-2)
APC/Cyanine7 anti-human CD303 (BDCA-2)
TotalSeq™-D0370 anti-human CD303 (BDCA-2)
Alexa Fluor® 700 anti-human CD303 (BDCA-2)
TotalSeq™-B0370 anti-human CD303 (BDCA-2)
Brilliant Violet 510™ anti-human CD303 (BDCA-2)
Purified anti-human CD303 (BDCA-2)
PE anti-human CD303 (BDCA-2)
Alexa Fluor® 647 anti-human CD303 (BDCA-2)
Alexa Fluor® 488 anti-human CD303 (BDCA-2)
APC/Fire™ 750 anti-human CD303 (BDCA-2)
Brilliant Violet 421™ anti-human CD303 (BDCA-2)
Brilliant Violet 711™ anti-human CD303 (BDCA-2)
PE/Cyanine7 anti-human CD303 (BDCA-2)
PE/Dazzle™ 594 anti-human CD303 (BDCA-2)
TotalSeq™-A0370 anti-human CD303 (BDCA-2)