Purified anti-human CD300F Recombinant Antibody

Pricing & Availability
Clone
QA19A86 (See other available formats)
Regulatory Status
RUO
Other Names
CD300LF, IREM-1, IgSF13
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA19A86_PURE_CD300F_RECOM_Antibody_080321.png
Human peripheral blood monocytes were stained with purified anti-human CD300T recombinant (clone QA19A86) (filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by goat-anti-mouse IgG PE.
  • QA19A86_PURE_CD300F_RECOM_Antibody_080321.png
    Human peripheral blood monocytes were stained with purified anti-human CD300T recombinant (clone QA19A86) (filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by goat-anti-mouse IgG PE.
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332602 100 µg 276,00€
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Description

IREM-1 (immune receptor expressed by myeloid cell 1) is a type I single transmembrane protein encoded by human chromosome 17q24.25. A member of the CD300 (CMRF-35) family and the Ig superfamily, IREM-1 is also known as CD300F, or CD300LF (CD300-like member F). CD300F is expressed on monocytes, granulocytes, and myeloid leukemia cell lines. The cytoplasmic domain of IREM-1 contains an ITIM and associates with the P85α subunit of PI3K (phosphoinositide 3-kinase). IREM-1 also functions as an inhibitory receptor.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone QA19A86 can completely block the binding of clone UP-D2 on target cells.

Product Citations
RRID
AB_2894680 (BioLegend Cat. No. 332602)

Antigen Details

Structure
Type I single transmembrane protein with cytoplamic ITIM, associates with p85α of PI3K, Ig superfamily
Distribution

Monocytes, granulocytes, and myeloid leukemia cell lines

Function
Inhibition of myeloid function
Interaction
Human
Cell Type
Granulocytes, Leukemia, Monocytes
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References
  1. Meyaard L, et al. 2008. J Leukoc Biol. 83:799.
  2. Lebbink RJ, et al. 2006. J Exp Med. 203:1419.
Gene ID
146722 View all products for this Gene ID
UniProt
View information about CD300F on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 08.03.2021

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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