Purified anti-human CD18 Antibody

Pricing & Availability
TS1/18 (See other available formats)
Regulatory Status
V AS162
Other Names
Integrin β2 subunit, LFA -1 β subunit, β2 integrin, ITGB2
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with purified TS1/18, followed by anti-mouse IgGs FITC
  • TS1slash18_Purified_061807
    Human peripheral blood lymphocytes stained with purified TS1/18, followed by anti-mouse IgGs FITC
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302102 100 µg 90€
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CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Reported Reactivity
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
Block - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: inhibition of cell adhesion and migration3,4. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 302116) is recommended for functional assays.

Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. 1995. Leucocyte Typing V. Oxford University Press. New York.
  2. Kishimoto T, et al. 1997. Leucocyte Typing VI. Garland Press. London.
  3. Van Epps DE, et al. 1989. J. Immunol. 143:3207. (Block)
  4. Meerschaert J, et al. 1994. J. Immunol. 152:1915. (Block)
  5. Sithu SD, et al. 2007. J. Biol. Chem. doi:10.1074/jbc.M611273200.
  6. Sommaggio R, et al. 2012. J. Immunol. 188:2075. PubMed
  7. Valenzuela NM, et al. 2013. J. Immunol. 190:6635. PubMed
Product Citations
  1. Hosoki K, et al. 2012. J Leukoc Biol. 92:333. PubMed
  2. Nakayama H, et al. 2008. J Leukoc Biol. 83:728. PubMed
  3. Sommaggio R, et al. 2012. J Immunol. 188:2075. PubMed
  4. Tran D, et al. 2009. J Immunol. 182:2929. PubMed
  5. Kolev M, et al. 2020. Immunity. 52(3):513-527. PubMed
  6. Chakrabarty S, et al. 2011. Blood. 117:1585. PubMed
AB_314220 (BioLegend Cat. No. 302102)

Antigen Details

Integrin, type I transmembrane glycoprotein, associates with CD11a, CD11b, or CD11c, 90-95 kD


Adhesion and signaling in hematopoietic system
Cell Type
Leukocytes, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Anderson D, et al. 1987. Annu. Rev. Med. 38:175.
2. Springer T. 1994. Cell 76:301.

Gene ID
3689 View all products for this Gene ID
View information about CD18 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 09.02.2022

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • FITC anti-human CD18

  • PE anti-human CD18

  • PE/Cyanine5 anti-human CD18

  • Purified anti-human CD18

  • APC anti-human CD18

  • Ultra-LEAF™ Purified anti-human CD18

  • PE/Cyanine7 anti-human CD18

  • PerCP/Cyanine5.5 anti-human CD18

  • PE/Dazzle™ 594 anti-human CD18

  • TotalSeq™-A0385 anti-human CD18

  • Alexa Fluor® 700 anti-human CD18

  • APC/Fire™ 750 anti-human CD18

  • TotalSeq™-C0385 anti-human CD18

  • TotalSeq™-B0385 anti-human CD18

  • APC/Cyanine7 anti-human CD18


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