Purified anti-human CCR10 Antibody

Pricing & Availability
6588-5 (See other available formats)
Regulatory Status
Other Names
GPR-2, C-C chemokine receptor 10
Armenian Hamster IgG
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Product Citations
Human peripheral blood lymphocytes stained with CD3 APC and purified 6588-5 conjugated with PE
  • A_6588-5_PE_050109.jpg
    Human peripheral blood lymphocytes stained with CD3 APC and purified 6588-5 conjugated with PE
  • B_6588-5_PE_050109.jpg
    Human peripheral blood lymphocytes stained with CLA (HECA-452) FITC and purified 6588-5 conjugated with PE (dot plot analysis is derived from CD3+ cell population)
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341502 100 µg 156,00€
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CCR10, also known as GPR-2, is a G-protein-coupled seven transmembrane CC-chemokine receptor. It is the receptor of CCL27 (CTACK/ALP/ILC/ESkine) and CCL28 (MEC) and is expressed on a small subset of T memory cells, IgA-secreting cells, EBV-immortalized B cells, dermal microvascular endothelial cells and dermal fibroblasts. The interaction of CCR10 with its ligands plays a role in the regulation of T cell homing into cutaneous site and IgA-secreting cells migration.

Product Details
Technical Data Sheet (pdf)

Product Details

Human, African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Host Species
Armenian Hamster
N-terminal peptide of human CCR10
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

It has been observed that clone 6588-5 can interact with some tandem-dye antibody conjugates during multi-color staining, potentially leading to unwanted staining. These dyes include PE/Cy7, PE/Cy5, PE/Dazzle™ 594, APC/Cy7, APC/Fire™ 750, and PerCP/Cy5.5.  This interaction can be resolved by sequentially staining with the 6588-5 antibody first and then followed by other antibodies of interest.

Product Citations
  1. Kaufmann M, et al. 2021. Med. 2(3):296-312.e8. PubMed
AB_1595419 (BioLegend Cat. No. 341502)

Antigen Details

G-protein-coupled seven transmembrane protein

Small subsets of T memory cells and IgA-secreting cells, EBV-immortalized B cells, dermal microvascular endothelial cells and dermal fibroblasts

T cell homing into cutaneous site, regulation of IgA-secreting cells migration
Cell Type
B cells, Endothelial cells, Fibroblasts, T cells
Biology Area
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Hudak S, et al. 2002. J. Immunol. 169:1189
2. Kunkel EJ, et al. 2003. J. Clin. Invest. 111:1001
3. Homey B, et al. 2002. Nature Medicine. 8:157
4. Nakayama T, et al. 2002. J. Virol. 76:3072

Gene ID
2826 View all products for this Gene ID
View information about CCR10 on UniProt.org

Related FAQs

Does staining at room temperature or even at 37°C help for checking chemokine receptors expression?

Due to continuous recycling of many chemokine receptors, it may be worthwhile to consider staining at room temperature or at 37°C if the staining at lower temperature (which can potentially reduce receptor turnover) is not optimal.

Go To Top Version: 3    Revision Date: 08.04.2017

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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