- N103/39 (See other available formats)
- Regulatory Status
- Other Names
- Mouse IgG1, κ
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- Product Citations
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Aldehyde dehydrogenase family 1 member L1 (ALDH1L1) was originally discovered as an enzyme that catalyzes the conversion of 10-formyltetrahydrofolate to tetrahydrofolate, with NADPH and CO2 as by products. ALDH1L1 is most exclusively expressed by astroglial cells1 implicating these cells as the major components of folate-dependent formate oxidation in the brain.Product Details
- Human, Mouse
- Antibody Type
- Host Species
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
WB - Quality tested
ICC, IHC-F - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 5.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant) formats include immunocytochemistry3 and immunohistochemistry on frozen tissue sections1.
(PubMed link indicates BioLegend citation)
- Zuo H, et al. 2018. J Neurosci. 38(9):2359 (IHC-F)
- Kidana K, et al. 2018. EMBO Mol Med. 10:e8184 (WB)
- Tian E, et al. 2016. Cell Reports. 16:781 (ICC)
AB_2783463 (BioLegend Cat. No. 856801)
AB_2783464 (BioLegend Cat. No. 856802)
- ALDH1L1 is a 902 amino acid protein with an apparent molecular mass of ~ 99 kD.
Tissue Distribution: Brain, Liver, Colon, and Kidney.
Cellular Distribution: Extracellular, cytosol, and plamsa membrane.
- ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate to tetrahydrofolate.
- Biology Area
- Cell Biology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
- Antigen References
- Neymerer V, et al. 1997. Brain Res. 766(1-2): 195
- Brandebura AN, et al. 2018. Dev Neurobiol. doi: 10.1002/dneu.22633.
- Garwood CJ, et al. 2017. Neuropathol Appl Neurobiol. 43(4):281
- Gene ID
- 10840 View all products for this Gene ID 107747 View all products for this Gene ID
- View information about ALDH1L1 on UniProt.org
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