PE anti-mouse IFN-γR β chain Antibody

Pricing & Availability
MOB-47 (See other available formats)
Regulatory Status
Other Names
IFN-γ Receptor β chain, IFN-γ AF-1
Armenian Hamster IgG
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Product Citations
A20 B cell line stained with MOB-47 PE
  • MOB-47
    A20 B cell line stained with MOB-47 PE
See PE spectral data
Cat # Size Price Quantity Check Availability Save
113603 50 µg 98€
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113604 200 µg 283€
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IFN-γ receptor β chain is also known as IFN-γ AF-1. This 60-65 kD class II cytokine receptor pairs with CDw119 to form the IFN-γ receptor. CDw119 serves as the IFN-γ-binding chain and associates with the IFN-γ β chain which is required for receptor signaling. The extracellular portion of both the IFN-γ receptor α and β chains must be species matched. The IFN-γ receptor β chain is expressed at low levels on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Armenian Hamster
Mouse IFN-γR β chain protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: Western blotting1 and immunoprecipitation1. For the most successful immunofluorescent staining results, it may be necessary to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 113604) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-Armenian hamster IgG (Cat. No. 405501) second step, followed by SAv-PE (Cat. No. 405204)).

Application References

(PubMed link indicates BioLegend citation)
  1. Bach EA, et al. 1995. Science 270:1215.
Product Citations
  1. Su Y, et al. 2022. J Hematol Oncol. 15:99. PubMed
  2. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  3. Lu Y, et al. 2019. Int J Mol Med. 43:2398. PubMed
  4. Tuttle KD, et al. 2020. Cell Rep. 33:108407. PubMed
  5. Ji L et al. 2019. Immunity. 51(2):272-284 . PubMed
  6. Shou P, et al. 2016. Oncogene. 10.1038/onc.2016.128. PubMed
AB_313560 (BioLegend Cat. No. 113603)
AB_313561 (BioLegend Cat. No. 113604)

Antigen Details

Class II cytokine receptor family, associates with CDw119, 60-65 kD, AF-1

T and B cells, NK cells, monocytes, macrophages, granulocytes, fibroblasts

Regulates immune response, upregulates MHC class I expression
Cell Type
B cells, Fibroblasts, Granulocytes, Macrophages, Monocytes, NK cells, T cells
Biology Area
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References

1. Bach EA, et al. 1995. Science 270:1215. 
2. Ansel KM, et al. 2003. Nat. Immunol. 4:616.

Gene ID
15978 View all products for this Gene ID
View information about IFN-gamma R beta chain on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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