PE anti-human IL12RB2 Antibody

Pricing & Availability
Clone
S16020B (See other available formats)
Regulatory Status
RUO
Other Names
Interleukin-12 receptor subunit beta-2
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
S16020B_PE_IL12RB2-_Antibody_091521.png
Human peripheral blood lymphocytes were activated for 3 days with PHA, and then stained with IL12RB2 (clone S16020B) PE, filled histogram) or mouse IgG2a, κ PE isotype control (open histogram).
  • S16020B_PE_IL12RB2-_Antibody_091521.png
    Human peripheral blood lymphocytes were activated for 3 days with PHA, and then stained with IL12RB2 (clone S16020B) PE, filled histogram) or mouse IgG2a, κ PE isotype control (open histogram).
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394205 25 tests 115€
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394206 100 tests 238€
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Description

IL12RB2 is a type I transmembrane protein that foms an heterodimer with IL12RB1 to produce the high affinity IL-12 receptor complex. IL12RB2 is expressed by activated T cells, TH1 cells, NK cells, B cells and plasma cells. Variants of this gene are associated with predisposition to various immune-related diseases.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human IL12RB2 transfected cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2894504 (BioLegend Cat. No. 394205)
AB_2894504 (BioLegend Cat. No. 394206)

Antigen Details

Structure
Type I transmembrane protein, 3 isoforms, foms an heterodimer with IL12RB1
Distribution

Activated T cells, TH1 cells, NK cells, B cells,  plasma cells

Function
Role in TH1 differentiation
Ligand/Receptor
IL-12
Cell Type
B cells, NK cells, Plasma cells, T cells, Th1
Biology Area
Immunology
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
  1. LaMere SA, et al. 2017. J Immunol. 199:3158
  2. Prigione I, et al. 2016. Immunobiology. 221:291
  3. de Paus RA, et al. 2013. Mol Immunol. 56:380
  4. Airoldi I, et al. 2008. Blood. 112:750
Gene ID
3595 View all products for this Gene ID
UniProt
View information about IL12RB2 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 09.16.2021

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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