- UP-H2 (See other available formats)
- Regulatory Status
- Other Names
- CD300e, CMRF35-A5, LMIR6
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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IREM-2 (immune receptor expressed by myeloid cells 2), also known as CMRF35-A5, LMIR6, CD300Le or CD300e, is a 34 kD type I single transmembrane glycoprotein. It is a member of the CD300 family and of the Ig-superfamily. IREM-2 is expressed on monocyte and myeloid dendritic cells, but not on granulocytes and lymphoid dendritic cells. IREM-2 is an activating receptor through interaction with DAP12.Product Details
- Antibody Type
- Host Species
- IREM-IgG fusion protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications include: immunoprecipitation and stimulation of TNF-a production by monocytes
(PubMed link indicates BioLegend citation)
- Aguilar H, et al. 2004. J. Immunol. 173:6703
- Gasiorowski RE, et al. 2013. Immunol Lett. 149:93. PubMed
- Product Citations
AB_2074099 (BioLegend Cat. No. 339704)
- 34 kD, type I transmembrane glycoprotein, CD300 family, Ig superfamily
- Monocytes, macrophages, dendritic cells
- Activation of myeloid cells
- Cell Type
- Monocytes, Macrophages, Dendritic cells
- Biology Area
- Molecular Family
- CD Molecules
- Antigen References
1. Aguilar H, et al. 2004. J. Immunol. 173:6703
- Gene ID
- 342510 View all products for this Gene ID
- View information about CD300e on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
|PE anti-human CD300e (IREM-2, CMRF35-A5)||UP-H2||FC|
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