- A17080A (See other available formats)
- Regulatory Status
- Other Names
- SYN, Synapsin, Synapsin I, Synapsin II, Synapsin III
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
|Cat #||Size||Price||Quantity Check Availability||Save|
Synapsins are a family of proteins involved in neurotransmitter release at the chemical synapses. Synapsins anchor synaptic vesicles to the cytoskeletal structures at the presynaptic terminal. Upon receiving an action potential, phosphorylation of synapsins, possibly by PKA, leads to the release of synaptic vesicles from cytoskeletal structures. This allows membrane docking and fusion of synaptic vesicles with the presynaptic membrane and neurotransmitter release.Product Details
- Verified Reactivity
- Human, Rat
- Antibody Type
- Host Species
- Recombinant protein corresponding to amino acids 362-450 of human Synapsin I
- This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
- The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.001 - 0.005 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2801202 (BioLegend Cat. No. 853703)
- Synapsin I is a 704 amino acid protein with an apparent molecular mass of ~74 kD. Synapsin II is a 582 amino acid protein with an apparent molecular mass of ~63 kD. Synapsin III is a 580 amino acid protein with an apparent molecular mass of ~63 kD.
Tissue distribution: Mainly in the central nervous system. Also expressed in testis.
Cellular distribution: Cytosol, nucleus, and plasma membrane.
- Synapsins are involved in the regulation of synaptic vesicle fusion and neurotransmitter release at the presynaptic terminals.
- CAPON (Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein), PKA
- Cell Type
- Biology Area
- Cell Biology, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
- Molecular Family
- Presynaptic proteins, Synaptic Vesicle Trafficking/Endocytosis
- Antigen References
- Greengard P, et al. 1993. Science. 259(5096):780
- Milovanovic D, et al. 2017. Neuron. 93(5):995
- Evergren E, et al. 2007. J. Neurosci. Res. 85(12):2648
- Gene ID
- 6853 View all products for this Gene ID 6854 View all products for this Gene ID 8224 View all products for this Gene ID
- View information about Synapsin I/II/III on UniProt.org
|Purified anti-Synapsin I/II/III||A17080A||WB, IHC-P|
|HRP anti-Synapsin I/II/III||A17080A||WB|
|Biotin anti-Synapsin I/II/III||A17080A||WB, IHC-P|
|Alexa Fluor® 594 anti-Synapsin I/II/III||A17080A||IHC-P|
|Alexa Fluor® 488 anti-Synapsin I/II/III||A17080A||IHC-P|
|Alexa Fluor® 647 anti-Synapsin I/II/III||A17080A||IHC-P|
|Spark YG™ 570 anti-Synapsin I/II/III Antibody||A17080A||IHC-P|
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.