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FITC anti-mouse TCR Vβ11 Antibody

Pricing & Availability
Clone
KT11 (See other available formats)
Regulatory Status
RUO
Other Names
T cell receptor Vβ 11 [vb11]
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
KT11_FITC_092308.jpg
C57BL/6 splenocytes stained with CD3 (145-2C11) APC and KT11 FITC
  • KT11_FITC_092308.jpg
    C57BL/6 splenocytes stained with CD3 (145-2C11) APC and KT11 FITC
Compare all formats See FITC spectral data
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125905 100 µg 123€
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Description

The Vβ11 gene locus is deleted in mice of TCR a haplotype (C57BR, C57L, SJL, SWR) and TCR c haplotype (RIII).Mice of TCR b haplotype (C57BL, BALB/c, AKR, etc) have Vβ11-bearing T cells .However, mice expressing MHC class II I-E and some superantigens, such as Mtv-8, Mtv-9 and Mtv-11 will show a partial deletion of Tb11-bearing T cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Quigley MF, et al. 2010. Proc Natl Acad Sci USA. 9:19414. PubMed
Product Citations
  1. Dangi T, et al. 2021. J Clin Invest. :e151969. PubMed
  2. Mohammed RN, et al. 2019. Sci Rep. 4.185416667. PubMed
RRID
AB_1227780 (BioLegend Cat. No. 125905)

Antigen Details

Distribution

Positive on a subset of alpha/beta T cells

Ligand/Receptor
MHC/peptide
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Gene ID
21577 View all products for this Gene ID
UniProt
View information about TCR Vbeta11 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11.30.2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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