Biotin anti-mouse CD102 Antibody

Pricing & Availability
3C4 (MIC2/4) (See other available formats)
Regulatory Status
Other Names
Rat IgG2a, κ
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Product Citations
C57BL/6 mouse splenocytes stained with biotinylated 3C4, followed by Sav-PE
  • 3C4_Biotin_083107
    C57BL/6 mouse splenocytes stained with biotinylated 3C4, followed by Sav-PE
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105604 500 µg 216€
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Description CD102 is a 55 kD immunoglobulin superfamily member, also known as ICAM-2. CD102 is a heavily glycosylated cell surface ligand for LFA-1 (CD11a/CD18). CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and T cell activation. The 3C4(MIC2/4) antibody can block interactions between ICAM-2 and LFA-1. Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
COS cells transfected with mouse ICAM-2 cDNA
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining2 of acetone-fixed frozen sections, in vitro blocking of ligand binding1, and immunoprecipitation1. The LEAF™ purified antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 105608).

Application References

(PubMed link indicates BioLegend citation)
  1. Xu H, et al. 1996. J. Immunol. 156:4909.
  2. Gerwin N, et al. 1999. Immunity 10:9.
Product Citations
  1. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  2. Ise W, et al. 2018. Immunity. 48:702. PubMed
AB_313197 (BioLegend Cat. No. 105604)

Antigen Details

Ig superfamily, 55 kD
Vascular endothelial cells, some resting lymphocytes, monocytes, platelets
Lymphocyte recirculation, costimulation
LFA-1, Mac-1
Cell Type
Endothelial cells, Lymphocytes, Monocytes, Platelets
Biology Area
Cell Adhesion, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Casasnovas JM, et al. 1999. P. Natl. Acad. Sci. USA 96:3017.
3. Diamond MS, et al. 1990. J. Cell Biol. 111:3129.
Gene ID
15896 View all products for this Gene ID
View information about CD102 on

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 1    Revision Date: 11.30.2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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